{"id":"W2789594768","doi":"10.3389/fimmu.2018.00345","title":"Virus-Like Particle, Liposome, and Polymeric Particle-Based Vaccines against HIV-1","year":2018,"lang":"en","type":"review","venue":"Frontiers in Immunology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Liposome; Virology; Particle (ecology); Human immunodeficiency virus (HIV); Virus-like particle; Virus; Materials science; Medicine; Nanotechnology; Chemistry; Biology; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002819634,0.0006230123,0.001960857,0.0004120725,0.0002191802,0.00003308512,0.0005189338,0.0008823122,0.0002720772],"category_scores_gemma":[0.0001182817,0.0005034473,0.0002898272,0.0005508864,0.0009198432,0.00009072618,0.0002474785,0.0007571812,0.002430355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001992397,"about_ca_system_score_gemma":0.0003713269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008042844,"about_ca_topic_score_gemma":0.00004464854,"domain_scores_codex":[0.9960719,0.001037852,0.000814433,0.0008217758,0.00005354683,0.001200493],"domain_scores_gemma":[0.9985735,0.000247976,0.0002796008,0.0007756679,0.00005034983,0.0000728715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003226039,0.0004760987,0.002625595,0.0009371263,0.0018567,0.0001215327,0.0001141177,2.644009e-7,0.0003042406,0.00004033196,0.02604125,0.9671601],"study_design_scores_gemma":[0.002415509,0.0004964463,0.0002826471,0.0009956652,0.0003217727,0.00006774084,0.00006457325,0.000005086508,0.0004778276,0.00001955286,0.9943972,0.0004560067],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002714465,0.9935337,0.0001008898,0.0001109917,0.002165043,0.0008655902,0.0002615406,0.00009539129,0.0001523776],"genre_scores_gemma":[0.000779817,0.9950672,0.0002847552,0.0001017164,0.000058937,0.0004582656,0.0009421963,0.0000708842,0.002236228],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9683559,"threshold_uncertainty_score":0.9997417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01945424640804684,"score_gpt":0.2753523463536616,"score_spread":0.2558980999456148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}