{"id":"W2789598128","doi":"10.3389/fnbeh.2018.00042","title":"Chronic Stress Alters Behavior in the Forced Swim Test and Underlying Neural Activity in Animals Exposed to Alcohol Prenatally: Sex- and Time-Dependent Effects","year":2018,"lang":"en","type":"article","venue":"Frontiers in Behavioral Neuroscience","topic":"Prenatal Substance Exposure Effects","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Mental Health & Substance Use Services; University of British Columbia","funders":"National Institute on Alcohol Abuse and Alcoholism; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Kids Brain Health Network; Canadian Foundation on Fetal Alcohol Research","keywords":"Amygdala; Behavioural despair test; Prefrontal cortex; Offspring; Prenatal stress; Endocrinology; Internal medicine; Hippocampal formation; Hypothalamus; Elevated plus maze; Psychology; Chronic stress; Hippocampus; Neuroscience; Medicine; Biology; Pregnancy; Psychiatry; Anxiety","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005975581,0.0003273956,0.000459688,0.0004123189,0.0001277338,0.000121043,0.000406497,0.0001176502,0.00000207553],"category_scores_gemma":[0.0002579633,0.0002740441,0.00003754989,0.0007980287,0.0004879877,0.0004924068,0.0002297793,0.0005049092,0.000001733425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003073681,"about_ca_system_score_gemma":0.00008110188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001325013,"about_ca_topic_score_gemma":0.0004870437,"domain_scores_codex":[0.997241,0.0002630542,0.0003102885,0.0009084372,0.0005454186,0.000731844],"domain_scores_gemma":[0.9990254,0.0001851114,0.0000962641,0.0004489349,0.00002446879,0.0002198084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001165482,0.0001858356,0.5092856,0.00004283484,5.19208e-7,0.0004343936,0.0006593573,0.00001075672,0.4768319,7.383732e-7,0.00002063462,0.01241087],"study_design_scores_gemma":[0.002137522,0.003034557,0.8937224,0.0002277676,0.00002967021,0.00007866324,0.0001329171,0.003008915,0.09735609,0.000006832257,0.000005353458,0.0002593854],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962704,0.0002770992,0.0001610724,0.0001543389,0.0005021012,0.002547138,0.00002479094,0.00004626352,0.00001683788],"genre_scores_gemma":[0.999037,0.00001799027,0.0003450222,0.0002236834,0.00004759763,0.0002589126,0.000002996146,0.00003109527,0.00003567137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3844368,"threshold_uncertainty_score":0.9999712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03471924045534266,"score_gpt":0.3162575735793837,"score_spread":0.2815383331240411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}