{"id":"W2789643871","doi":"10.1016/j.aquatox.2018.02.006","title":"Gemfibrozil and carbamazepine decrease steroid production in zebrafish testes ( Danio rerio )","year":2018,"lang":"en","type":"article","venue":"Aquatic Toxicology","topic":"Pharmaceutical and Antibiotic Environmental Impacts","field":"Environmental Science","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto; McMaster University","funders":"Trent University; McMaster University","keywords":"Gemfibrozil; Pregnenolone; Internal medicine; Endocrinology; Zebrafish; Carbamazepine; Testosterone (patch); Androgen; Danio; Biology; In vivo; Chemistry; Steroid; Cholesterol; Medicine; Hormone; Biochemistry; Epilepsy; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012643,0.0004127851,0.000325682,0.0005205513,0.000284097,0.0002678672,0.0002484558,0.0004919241,0.003742832],"category_scores_gemma":[0.0001965719,0.0002861862,0.0005850248,0.0002047217,0.0004533428,0.0003105673,0.0002118094,0.0007122073,0.0004092147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006292963,"about_ca_system_score_gemma":0.0006812438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01144427,"about_ca_topic_score_gemma":0.02168047,"domain_scores_codex":[0.9998603,0.00001230292,0.00001392897,0.00002895138,0.00002990626,0.00005458597],"domain_scores_gemma":[0.9998249,0.00002070402,0.00004652291,0.00002000456,0.0000318925,0.00005597757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001059735,0.00003929852,0.0006876593,0.00004338672,0.00001622397,0.000138856,0.00003990059,0.00004041577,0.9966293,0.00006010657,0.0001519959,0.001093024],"study_design_scores_gemma":[0.0000719714,0.0007353509,0.01580873,0.000006019721,0.00005626813,0.0001582825,0.0001618021,0.0002163849,0.9812122,0.00004099305,0.001518531,0.0000134371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954223,0.0009734535,0.0004632793,0.0003079978,0.00005897197,0.0000227296,0.0009965305,0.0001320138,0.00162275],"genre_scores_gemma":[0.9896311,0.0006453933,0.0008436068,0.0001144805,0.00001229653,0.00003796848,0.000729736,0.00002730847,0.007958292],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01144427,"threshold_uncertainty_score":0.02275532,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01914149251346644,"score_gpt":0.2709200193469606,"score_spread":0.2517785268334942,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}