{"id":"W2789688210","doi":"10.1016/j.lungcan.2018.03.009","title":"Malignant cells from pleural fluids in malignant mesothelioma patients reveal novel mutations","year":2018,"lang":"en","type":"article","venue":"Lung Cancer","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"","keywords":"CDKN2A; Mesothelioma; BAP1; Medicine; Pleural effusion; Pathology; Exome sequencing; Mutation; Somatic cell; Cancer research; Malignant pleural effusion; Pleural disease; Cancer; Gene; Biology; Lung; Respiratory disease; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000143693,0.0004752619,0.0002518719,0.001289972,0.0004893256,0.0008987834,0.0003574319,0.0008225921,0.003157249],"category_scores_gemma":[0.001134098,0.0002139021,0.0003282176,0.0006070302,0.000341333,0.0002825737,0.0004472229,0.0002798351,0.0008175284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001886616,"about_ca_system_score_gemma":0.0001140939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007851335,"about_ca_topic_score_gemma":0.0007553959,"domain_scores_codex":[0.9997333,0.00002313916,0.00004210091,0.00005832237,0.00008414734,0.00005908176],"domain_scores_gemma":[0.9997014,0.0000915894,0.00006834607,0.00003190663,0.00005644774,0.00005030309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001099786,0.00009916283,0.4007384,0.000152287,0.0001509455,0.02771518,0.0009663437,0.0003506885,0.5396643,0.0003322602,0.00155812,0.02717255],"study_design_scores_gemma":[0.00006177265,0.0002845045,0.7729422,0.00005490973,0.0003264468,0.09085713,0.001155073,0.001755037,0.1232023,0.0007352374,0.008594132,0.00003119143],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959832,0.0009308704,0.0004571662,0.0001335281,0.00003050274,0.00001202289,0.0007488057,0.0000541249,0.001649795],"genre_scores_gemma":[0.9985059,0.0002072107,0.0003327045,0.00004091955,0.00001770212,0.000006481195,0.0004266249,0.00001300988,0.000449456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003157249,"threshold_uncertainty_score":0.01056206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01181235053123601,"score_gpt":0.280764804200338,"score_spread":0.268952453669102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}