{"id":"W2789688210","doi":"10.1016/j.lungcan.2018.03.009","title":"Malignant cells from pleural fluids in malignant mesothelioma patients reveal novel mutations","year":2018,"lang":"en","type":"article","venue":"Lung Cancer","topic":"Occupational and environmental lung diseases","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"","keywords":"CDKN2A; Mesothelioma; BAP1; Medicine; Pleural effusion; Pathology; Exome sequencing; Mutation; Somatic cell; Cancer research; Malignant pleural effusion; Pleural disease; Cancer; Gene; Biology; Lung; Respiratory disease; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00003153875,0.000135408,0.0001688217,0.00007261788,0.00005989126,0.00001060485,0.00006848946,0.00005266661,0.001330572],"category_scores_gemma":[0.00001123718,0.0001106842,0.0000606582,0.0001436208,0.00009873696,0.00008518195,0.00003952419,0.000062183,0.0001249669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002517476,"about_ca_system_score_gemma":0.0000671559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001408674,"about_ca_topic_score_gemma":0.0002181677,"domain_scores_codex":[0.9989695,0.00001541964,0.000233634,0.0002743237,0.000284492,0.000222664],"domain_scores_gemma":[0.999588,0.00002712045,0.00005137286,0.0001696352,0.00003811066,0.000125779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003089893,0.0004259739,0.9078584,0.00003320395,0.00005825584,0.00001427328,0.0003976501,0.00002414812,0.08479162,0.00003490907,0.004980872,0.001071701],"study_design_scores_gemma":[0.001875061,0.0001321566,0.9768727,0.0002416649,0.00011203,0.000001078368,0.00005024665,0.0009341391,0.01787842,0.00005569032,0.001697844,0.0001489969],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970628,0.000376929,0.00004240563,0.0003165201,0.0004141329,0.0003123059,0.0007166663,0.00002557785,0.0007326807],"genre_scores_gemma":[0.9960249,0.00003221336,0.000653533,0.001028309,0.0003649979,0.00007367218,0.0003174251,0.00002371701,0.001481208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06901426,"threshold_uncertainty_score":0.9995824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01181235053123601,"score_gpt":0.280764804200338,"score_spread":0.268952453669102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}