{"id":"W2789735842","doi":"10.1111/liv.13714","title":"Comprehensive bile acid profiling in hereditary intrahepatic cholestasis: Genetic and clinical correlations","year":2018,"lang":"en","type":"article","venue":"Liver International","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Victoria; Jewish General Hospital; BC Cancer Agency","funders":"Canadian Institutes of Health Research; China Scholarship Council; Leading Edge Endowment Fund; National Natural Science Foundation of China","keywords":"Cholestasis; Bile acid; Progressive familial intrahepatic cholestasis; Internal medicine; Gastroenterology; Medicine; Computational biology; Biology; Liver transplantation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004461724,0.0004397511,0.0003036941,0.001050439,0.0002214105,0.0003426456,0.0001595193,0.0003439542,0.0009107171],"category_scores_gemma":[0.001120035,0.0001457762,0.0001959564,0.0007450162,0.000354364,0.0002024656,0.0004180247,0.0003010968,0.0001676224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002157249,"about_ca_system_score_gemma":0.0001504348,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005446813,"about_ca_topic_score_gemma":0.0006378237,"domain_scores_codex":[0.9997014,0.00007201704,0.00005060194,0.00008634441,0.00005439762,0.00003520068],"domain_scores_gemma":[0.9991111,0.0002153183,0.0003726255,0.00005899259,0.0001026318,0.0001392553],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003657317,0.00002385423,0.9833029,0.00002032253,0.00004815921,0.0008655358,0.00005446879,0.0001081287,0.01070231,0.00002437845,0.00004926452,0.00443498],"study_design_scores_gemma":[0.000007122433,0.0002039154,0.9898338,0.000005371231,0.00005594571,0.005100925,0.00006770246,0.0004822442,0.004007982,0.00007264673,0.0001564818,0.000005913811],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991406,0.0002799504,0.000295713,0.00001570525,0.000001613732,0.000004835959,0.00007107224,0.000009126879,0.0001812268],"genre_scores_gemma":[0.9993938,0.00008103816,0.0003623451,0.000009317037,0.000003699751,0.000002778763,0.00009837052,0.000002799639,0.00004590855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001050439,"threshold_uncertainty_score":0.003046691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03070498299596981,"score_gpt":0.313784346379572,"score_spread":0.2830793633836022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}