{"id":"W2789735842","doi":"10.1111/liv.13714","title":"Comprehensive bile acid profiling in hereditary intrahepatic cholestasis: Genetic and clinical correlations","year":2018,"lang":"en","type":"article","venue":"Liver International","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; University of Victoria; Jewish General Hospital; BC Cancer Agency","funders":"Canadian Institutes of Health Research; China Scholarship Council; Leading Edge Endowment Fund; National Natural Science Foundation of China","keywords":"Cholestasis; Bile acid; Progressive familial intrahepatic cholestasis; Internal medicine; Gastroenterology; Medicine; Computational biology; Biology; Liver transplantation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008088459,0.00009029443,0.0001543696,0.0001099566,0.00003908858,0.00001187248,0.00007586354,0.00007833565,0.0002559123],"category_scores_gemma":[0.00002747373,0.0000799684,0.00005170635,0.00008337291,0.0001643288,0.00006885293,0.00002571407,0.0001843517,0.00005496994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003659392,"about_ca_system_score_gemma":0.00005139434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003083226,"about_ca_topic_score_gemma":0.0001046406,"domain_scores_codex":[0.9991194,0.00002361003,0.0003142417,0.0002234791,0.0001978953,0.0001213485],"domain_scores_gemma":[0.999569,0.00004946297,0.000051615,0.0001077655,0.0001450547,0.00007707644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003885858,0.0004557958,0.966399,0.00007521744,0.0002152926,0.0004511401,0.0006688317,0.000009849586,0.002119133,0.001341362,0.0005063858,0.02736946],"study_design_scores_gemma":[0.001629203,0.0001985226,0.9861503,0.0001805953,0.00006221933,0.00008615041,0.0003317049,0.008000595,0.001133486,0.0004267496,0.001692747,0.0001077082],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939696,0.0003465225,0.002182351,0.0003903432,0.001129279,0.000238862,0.00002072936,0.00003068382,0.001691624],"genre_scores_gemma":[0.9860705,0.0001918931,0.01237288,0.0003774572,0.0006255538,0.00001226817,0.00006829135,0.00001148604,0.0002697207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02726175,"threshold_uncertainty_score":0.3261017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03070498299596981,"score_gpt":0.313784346379572,"score_spread":0.2830793633836022,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}