{"id":"W2789736722","doi":"10.1186/s12885-018-4087-1","title":"Assessing the performance of a Loop Mediated Isothermal Amplification (LAMP) assay for the detection and subtyping of high-risk suptypes of Human Papilloma Virus (HPV) for Oropharyngeal Squamous Cell Carcinoma (OPSCC) without DNA purification","year":2018,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary; University of Alberta","funders":"Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Loop-mediated isothermal amplification; Primer (cosmetics); Subtyping; Polymerase chain reaction; Carcinogenesis; Biology; Human papilloma virus; Molecular biology; DNA; Virology; Cancer research; Medicine; Cancer; Gene; Cervical cancer; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003716888,0.0001095831,0.0001837435,0.00005254422,0.0001799686,0.00002082989,0.00008917128,0.00008575636,0.00001166498],"category_scores_gemma":[0.00005234185,0.0000745293,0.00005788726,0.0001492377,0.0001470479,0.0001212076,0.000009058131,0.00007792925,3.558377e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004322312,"about_ca_system_score_gemma":0.00002381581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006498663,"about_ca_topic_score_gemma":0.0007574992,"domain_scores_codex":[0.9992513,0.0000410471,0.0003105562,0.000145291,0.0001114695,0.0001403273],"domain_scores_gemma":[0.9991019,0.0002598801,0.0002351306,0.000182423,0.0001990046,0.00002164317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001209213,0.00002037599,0.00763506,0.0004754633,0.00002331145,8.429928e-9,0.0002518836,0.0009735448,0.9693936,0.00004618314,0.000007035002,0.02105266],"study_design_scores_gemma":[0.0003934238,0.0001582216,0.1674689,0.00001697636,0.0001002911,3.15866e-7,0.00008431578,0.2340534,0.5975943,0.00001960443,0.00004384598,0.00006644759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9653086,0.0005063493,0.03347574,0.00001288492,0.0001511636,0.000454512,0.00004627436,0.000025488,0.00001899414],"genre_scores_gemma":[0.9993348,0.00007444365,0.0002471921,0.0000047209,0.0001863774,0.00009825936,0.000007136485,0.00002617832,0.00002092068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3717993,"threshold_uncertainty_score":0.3039217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02020821770458266,"score_gpt":0.2610574294256446,"score_spread":0.240849211721062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}