{"id":"W2789736722","doi":"10.1186/s12885-018-4087-1","title":"Assessing the performance of a Loop Mediated Isothermal Amplification (LAMP) assay for the detection and subtyping of high-risk suptypes of Human Papilloma Virus (HPV) for Oropharyngeal Squamous Cell Carcinoma (OPSCC) without DNA purification","year":2018,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Biosensors and Analytical Detection","field":"Engineering","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary; University of Alberta","funders":"Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Loop-mediated isothermal amplification; Primer (cosmetics); Subtyping; Polymerase chain reaction; Carcinogenesis; Biology; Human papilloma virus; Molecular biology; DNA; Virology; Cancer research; Medicine; Cancer; Gene; Cervical cancer; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001991692,0.0007617885,0.0004580447,0.0004706855,0.0002672531,0.0006659945,0.000613148,0.001181222,0.001090645],"category_scores_gemma":[0.002610053,0.0004520471,0.0006347023,0.0004254084,0.000412122,0.0005548103,0.0002754671,0.0005633447,0.0009127529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00059178,"about_ca_system_score_gemma":0.0003921516,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001202177,"about_ca_topic_score_gemma":0.00111284,"domain_scores_codex":[0.9977768,0.0006061927,0.0001891177,0.0005185721,0.00071561,0.0001936779],"domain_scores_gemma":[0.997928,0.0009679681,0.0002724789,0.0002259855,0.0005355716,0.00007006984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005298094,0.000309517,0.01039796,0.0002104544,0.00006407946,0.00004614691,0.0001016643,0.000912204,0.9794379,0.00004527905,0.0001029926,0.00784192],"study_design_scores_gemma":[0.00001003585,0.002098583,0.01382579,0.00001326733,0.00008384587,0.0002399459,0.00003668254,0.004802353,0.9781957,0.00002525093,0.0006488409,0.00001978503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9685023,0.001273433,0.02819589,0.00006237223,0.00004939205,0.0001506402,0.0003707438,0.000200146,0.001195052],"genre_scores_gemma":[0.9636717,0.0007203788,0.03283408,0.00007912783,0.00001728513,0.0001678483,0.001073884,0.00005324844,0.00138251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001991692,"threshold_uncertainty_score":0.01053321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02020821770458266,"score_gpt":0.2610574294256446,"score_spread":0.240849211721062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}