{"id":"W2789906712","doi":"10.2340/00015555-2893","title":"Early Relief of Pruritus in Atopic Dermatitis with Crisaborole Ointment, A Non-steroidal, Phosphodiesterase 4 Inhibitor","year":2018,"lang":"en","type":"article","venue":"Acta Dermato Venereologica","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Allergan; LEO Fondet; Eli Lilly and Company; AstraZeneca; Galderma; F. Hoffmann-La Roche; Incyte; Regeneron Pharmaceuticals; Kiniksa Pharmaceuticals; Celgene; Valeant Pharmaceuticals International; Sanofi; Pfizer","keywords":"Medicine; Atopic dermatitis; Exacerbation; Dermatology; Post-hoc analysis; Antipruritic; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001260833,0.0002049924,0.0006850224,0.0002311163,0.0001262938,0.0002330243,0.0001614888,0.0001612345,0.0019257],"category_scores_gemma":[0.0008403363,0.00008577159,0.0008084078,0.0001802556,0.0001535214,0.0002224005,0.0001261532,0.0005707137,0.0001432723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001713113,"about_ca_system_score_gemma":0.000292398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000212255,"about_ca_topic_score_gemma":0.0008589292,"domain_scores_codex":[0.9995085,0.0002923668,0.00003454208,0.00003438321,0.00007287601,0.00005726139],"domain_scores_gemma":[0.9995275,0.0002229202,0.0001297075,0.00003343709,0.0000289354,0.00005743964],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2340518,0.01081173,0.07271951,0.003934403,0.002939956,0.001196105,0.0001845782,0.001952855,0.1099696,0.0002976118,0.002138319,0.5598035],"study_design_scores_gemma":[0.03267625,0.5417633,0.3890371,0.0002335335,0.002456926,0.00324007,0.0001847099,0.001346887,0.02057012,0.0001979394,0.008260788,0.00003227946],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862634,0.01106822,0.0003718943,0.0001140495,0.00003718753,0.0003081351,0.0002638677,0.0000224368,0.001550846],"genre_scores_gemma":[0.996195,0.002480441,0.0003956372,0.00008979482,0.00003904631,0.00006072792,0.0002538662,0.000003197411,0.000482334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0019257,"threshold_uncertainty_score":0.006667972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009146717762985966,"score_gpt":0.2474725281939917,"score_spread":0.2383258104310058,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}