{"id":"W2789924966","doi":"10.1117/12.2290060","title":"Large scale serial two-photon microscopy to investigate local vascular changes in whole rodent brain models of Alzheimer's disease","year":2018,"lang":"en","type":"article","venue":"","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Polytechnique Montréal","funders":"","keywords":"Rodent; Rodent model; Microscopy; Disease; Neuroscience; Scale (ratio); Medicine; Pathology; Biology; Ecology; Geography; Cartography; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005240863,0.0004519107,0.0002845269,0.0007061852,0.0003073622,0.0002689663,0.0004142336,0.0003632815,0.001331551],"category_scores_gemma":[0.000280949,0.0003128633,0.0002505577,0.000308002,0.0002476157,0.0004486493,0.0003391574,0.0006304837,0.0002367147],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002634281,"about_ca_system_score_gemma":0.000334847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001337852,"about_ca_topic_score_gemma":0.003493813,"domain_scores_codex":[0.9998572,0.00002558393,0.0000068692,0.00003669554,0.0000526543,0.00002089252],"domain_scores_gemma":[0.9997465,0.00005800004,0.00004951067,0.00005813289,0.00006077518,0.00002717435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005909861,0.00004383759,0.0006660785,0.0000431104,0.00001435364,0.00005177265,0.00003318662,0.0004660108,0.9932737,0.0002537789,0.00008888332,0.00500627],"study_design_scores_gemma":[0.00004951083,0.001019538,0.05382236,0.00002612363,0.00009391454,0.00255932,0.000117891,0.01946637,0.9158728,0.001194405,0.005736177,0.00004163429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7211626,0.001532393,0.2735241,0.0001484645,0.00005428585,0.0001752163,0.0004840217,0.000690361,0.002228711],"genre_scores_gemma":[0.7422978,0.001566916,0.2510245,0.00008634156,0.00002416039,0.0003518269,0.0005200597,0.0002124018,0.003916042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001337852,"threshold_uncertainty_score":0.004454434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02909341520830261,"score_gpt":0.326576531345336,"score_spread":0.2974831161370334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}