{"id":"W2789961905","doi":"10.1074/mcp.ra117.000447","title":"Promyelocytic Leukemia Protein (PML) Requirement for Interferon-induced Global Cellular SUMOylation","year":2018,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université du Québec; Institute for Research in Immunology and Cancer","funders":"Natural Sciences and Engineering Research Council of Canada; Agence Nationale de Recherches sur le Sida et les Hépatites Virales; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Agence Nationale de la Recherche","keywords":"SUMO protein; Promyelocytic leukemia protein; Biology; Gene isoform; Acute promyelocytic leukemia; Interferon; RNA splicing; Cell biology; Nuclear protein; Alternative splicing; Molecular biology; Ubiquitin; Cell culture; Gene; Genetics; Retinoic acid; Transcription factor; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009167285,0.000249247,0.0001510725,0.0001444276,0.0001541616,0.0003195973,0.00009922745,0.0001245176,0.0007927521],"category_scores_gemma":[0.00007050333,0.00010058,0.0001715773,0.0001906121,0.0001486483,0.00016672,0.0002120094,0.0002686211,0.000363368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002404417,"about_ca_system_score_gemma":0.0002151167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001870663,"about_ca_topic_score_gemma":0.0004776655,"domain_scores_codex":[0.9999181,0.000009638468,0.000008570301,0.00002509799,0.00002165268,0.00001682648],"domain_scores_gemma":[0.9999466,0.000005400429,0.00001695038,0.00001052429,0.000006232054,0.00001431065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005746579,0.000007544229,0.0003878351,0.00001374646,0.000003651426,0.00004674061,0.000005128953,0.00002345937,0.9983246,0.0001085754,0.00001403468,0.001007131],"study_design_scores_gemma":[0.00001260323,0.00009144424,0.0181195,0.00000563056,0.00001986991,0.0008385351,0.00003028188,0.0005439805,0.9768422,0.0002372186,0.00325632,0.000002397058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950288,0.0008877186,0.002339842,0.00005881176,0.00001058105,0.00001072699,0.0004279069,0.00004445322,0.00119115],"genre_scores_gemma":[0.9954073,0.0005692783,0.001808779,0.00002167336,0.000004281305,0.00001529879,0.0007548478,0.00001028955,0.001408271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007927521,"threshold_uncertainty_score":0.002651989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01887355511250047,"score_gpt":0.2564164491250365,"score_spread":0.2375428940125361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}