{"id":"W2790046175","doi":"10.1128/mbio.02164-17","title":"Plasmid Negative Regulation of CPAF Expression Is Pgp4 Independent and Restricted to Invasive<i>Chlamydia trachomatis</i>Biovars","year":2018,"lang":"en","type":"article","venue":"mBio","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Agency of Canada","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Public Health Agency; Public Health Agency of Canada","keywords":"Chlamydia trachomatis; Biology; Plasmid; Microbiology; Biovar; Virulence; Lymphogranuloma venereum; Serotype; Trachoma; Virology; Tissue tropism; Tropism; Replicon; Virulence factor; Gene; Genetics; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002066364,0.0001401565,0.0002149811,0.0003033763,0.0002124377,0.00001774364,0.0001440263,0.0002323503,0.000914002],"category_scores_gemma":[0.0005291395,0.0001139985,0.00004028032,0.0003133361,0.0003701143,0.0001756735,0.0001464375,0.0002442563,0.0004552149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000574099,"about_ca_system_score_gemma":0.00006034933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002746029,"about_ca_topic_score_gemma":0.00005503227,"domain_scores_codex":[0.9986886,0.0002388158,0.0002880873,0.0004259869,0.00008625633,0.0002722997],"domain_scores_gemma":[0.9989168,0.0002092197,0.00009605072,0.0004002176,0.0003390508,0.00003866239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002440539,0.0001183963,0.009425361,0.00001579992,0.00006307071,9.145288e-7,0.00282276,0.000002462089,0.9792081,0.00008556018,0.005081051,0.002932485],"study_design_scores_gemma":[0.0004694019,0.0002070189,0.362268,0.00003432342,0.00000885629,0.00002057069,0.0001413579,0.000001000877,0.6350461,0.0003364789,0.001387711,0.00007916717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964765,0.0001167969,0.0002419774,0.0003271717,0.0002903655,0.0005120377,0.00003024427,0.00004275029,0.001962162],"genre_scores_gemma":[0.9977632,0.00002949934,0.0003651514,0.00006044515,0.00005119577,0.00003412387,0.00002729936,0.00001442544,0.001654655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3528426,"threshold_uncertainty_score":0.9999993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01860712035475695,"score_gpt":0.2776997887980046,"score_spread":0.2590926684432476,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}