{"id":"W2790087917","doi":"10.3390/genes9040179","title":"Resistance to 6-Methylpurine is Conferred by Defective Adenine Phosphoribosyltransferase in Tetrahymena","year":2018,"lang":"en","type":"article","venue":"Genes","topic":"Protist diversity and phylogeny","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Adenine phosphoribosyltransferase; Mutant; Biology; RNA interference; Tetrahymena; Locus (genetics); RNA; Molecular biology; Biochemistry; Genetics; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009166873,0.0001308139,0.0001229176,0.00003693841,0.00007237311,0.00001356092,0.0001887948,0.0001014352,0.0001125631],"category_scores_gemma":[0.00002644187,0.0001399641,0.00004609138,0.0001476834,0.00008113432,0.000002957282,0.00006777693,0.00005255331,0.00006231243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001617217,"about_ca_system_score_gemma":0.00003672365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001004122,"about_ca_topic_score_gemma":0.0005857013,"domain_scores_codex":[0.9991583,0.00003704473,0.0001152218,0.0003592947,0.00009124378,0.0002389008],"domain_scores_gemma":[0.9995602,0.000006749554,0.00001949801,0.0002391743,0.00007963867,0.00009472715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004645349,0.00006861635,0.02821026,0.00001215393,0.00003985981,0.000006693258,0.0002717839,0.000001084113,0.9386545,0.00004119129,0.03050712,0.001722218],"study_design_scores_gemma":[0.0004914443,0.0002702112,0.0116871,0.000008606185,0.000007151031,0.000001709845,0.00004003066,9.976927e-7,0.8569891,0.00008382377,0.1302515,0.0001683994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935166,0.002478587,0.001108178,0.0003892776,0.0001302264,0.0002502478,0.0002537154,0.00001009088,0.001863023],"genre_scores_gemma":[0.995663,0.0001847751,0.0005099253,0.0009322291,0.0001612818,0.00002187393,0.0000710711,0.00001197164,0.002443858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09974433,"threshold_uncertainty_score":0.570757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006577650913213712,"score_gpt":0.236115737935894,"score_spread":0.2295380870226802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}