{"id":"W2790119699","doi":"10.1093/jcag/gwy009.095","title":"A95 INFLAMMATORY PROTEASES DRIVE A MIGRATORY INTESTINAL EPITHELIAL PHENOTYPE THROUGH THE GENERATION OF BIOACTIVE PEPTIDE FRAGMENTS OF E-CADHERIN","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke; University of Calgary","funders":"","keywords":"Proteases; Wound healing; Cell biology; Neutrophil elastase; Chemistry; Biology; Biochemistry; Molecular biology; Inflammation; Immunology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000139939,0.0002676999,0.0001574023,0.0001807792,0.0001274411,0.0003350357,0.0001331502,0.000192728,0.002265756],"category_scores_gemma":[0.0001756824,0.0001189662,0.0002000682,0.0001508485,0.0001669738,0.0002244596,0.000125259,0.0004980884,0.0004313806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001611029,"about_ca_system_score_gemma":0.0001186994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002348392,"about_ca_topic_score_gemma":0.0004090764,"domain_scores_codex":[0.9998616,0.00002025917,0.00001520476,0.0000229268,0.0000498467,0.00003011936],"domain_scores_gemma":[0.9999052,0.00002658632,0.00002086732,0.00001465558,0.00001334789,0.00001929178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005146383,0.00001540069,0.0001153079,0.00001929095,0.00000227815,0.00002796786,0.000005899279,0.00002191804,0.998813,0.00003142107,0.00002463978,0.0008713761],"study_design_scores_gemma":[0.00002001593,0.0003250783,0.005424941,0.000006256512,0.000007975595,0.0003861037,0.00002897751,0.000519052,0.991122,0.00003903993,0.002116893,0.000003633936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934516,0.001457543,0.002508691,0.00008638939,0.00002223108,0.00002520866,0.000323621,0.00003902258,0.002085671],"genre_scores_gemma":[0.9897452,0.001181995,0.005206121,0.00008941362,0.00001089135,0.00002817353,0.000937723,0.00001221105,0.002788389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002265756,"threshold_uncertainty_score":0.007579684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01587903236560798,"score_gpt":0.2474606530795372,"score_spread":0.2315816207139292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}