{"id":"W2790153657","doi":"10.1155/2018/3074769","title":"Yeast Cells Exposed to Exogenous Palmitoleic Acid Either Adapt to Stress and Survive or Commit to Regulated Liponecrosis and Die","year":2018,"lang":"en","type":"review","venue":"Oxidative Medicine and Cellular Longevity","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"","keywords":"Lipotoxicity; Endoplasmic reticulum; Palmitoleic acid; Cell biology; Lipid droplet; Lipid metabolism; Biology; Programmed cell death; Peroxisome; Vacuole; Mitochondrion; Saccharomyces cerevisiae; Biochemistry; Yeast; Fatty acid; Linoleic acid; Apoptosis; Cytoplasm; Insulin; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005805358,0.0007465818,0.001689765,0.0001734325,0.0002322891,0.00006506732,0.0003279772,0.0004233418,0.00007711696],"category_scores_gemma":[0.0002647906,0.0004926135,0.0001152361,0.0002916717,0.0003131395,0.000008664229,0.0006102048,0.0001868175,0.00002873426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002036472,"about_ca_system_score_gemma":0.00009781469,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001492333,"about_ca_topic_score_gemma":0.0005864205,"domain_scores_codex":[0.9970497,0.0004215707,0.00055226,0.00119919,0.0002789968,0.000498297],"domain_scores_gemma":[0.997993,0.0000849644,0.00022353,0.0007504181,0.000179465,0.0007686333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003941012,0.0001760253,0.0000412165,0.004011795,0.00062429,0.00006837606,0.001394202,9.524345e-8,0.2574322,0.000002347518,0.004924195,0.7309311],"study_design_scores_gemma":[0.0003613092,0.0008980276,0.00007330604,0.002808472,0.000603935,0.00001480554,0.0002858375,3.246514e-7,0.2354631,8.973743e-7,0.7589254,0.0005646454],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1026667,0.8939908,0.0004783879,0.0001803526,0.0003081851,0.001689248,0.0004918473,0.00002058177,0.0001738725],"genre_scores_gemma":[0.01561282,0.9784454,0.0008353794,0.0005767671,0.001394606,0.0001428142,0.0004088671,0.0001225327,0.00246081],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7540012,"threshold_uncertainty_score":0.9997525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04605361288079207,"score_gpt":0.2893410369799684,"score_spread":0.2432874240991764,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}