{"id":"W2790232800","doi":"10.1093/jcag/gwy008.291","title":"A290 THE ATF6 ARM OF ER STRESS ANTAGONIZES METABOLIC STRESS-INDUCED DECREASES IN EPITHELIAL BARRIER FUNCTION TO COMMENSAL BACTERIA BY PROMOTING XENOPHAGY","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Calgary","funders":"","keywords":"Function (biology); Bacteria; Stress (linguistics); Cell biology; Unfolded protein response; Biology; Microbiology; Endoplasmic reticulum; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001831459,0.0003732309,0.000499806,0.000228149,0.0001869741,0.0003083895,0.0003593515,0.0005201497,0.004286213],"category_scores_gemma":[0.0001555171,0.0001680941,0.0003721238,0.0001977987,0.0003668143,0.0002776283,0.0002155653,0.001210414,0.0009982036],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001967052,"about_ca_system_score_gemma":0.0003257133,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005554177,"about_ca_topic_score_gemma":0.0007472193,"domain_scores_codex":[0.9998118,0.00003835169,0.0000319484,0.000032595,0.00003598508,0.000049333],"domain_scores_gemma":[0.9998091,0.00002792376,0.00003347216,0.00003117925,0.00001831239,0.00007999074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001542907,0.0003861117,0.00007684242,0.00008325034,0.00001290402,0.00005952187,0.00001930191,0.0001041224,0.9956297,0.0001387527,0.0002605734,0.001686035],"study_design_scores_gemma":[0.0002923068,0.003050338,0.00301951,0.00002128993,0.00002926994,0.0004241721,0.00009188549,0.002070663,0.9841137,0.0001847061,0.00668793,0.00001414954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917379,0.001219972,0.001635144,0.0004624974,0.000194115,0.00005937771,0.001395877,0.0002348613,0.003060192],"genre_scores_gemma":[0.991053,0.001045048,0.00183426,0.0002093749,0.00003517555,0.00009969034,0.001939066,0.00005557251,0.003728737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004286213,"threshold_uncertainty_score":0.01433879,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006276530185901723,"score_gpt":0.2323094574185943,"score_spread":0.2260329272326926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}