{"id":"W2790511686","doi":"","title":"Abstract 16560: Knock-Out of Canopy 2 Activates p16 Pathway to Impair Cardiac Regeneration","year":2016,"lang":"en","type":"article","venue":"","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Medicine; Angiogenesis; Cardiac function curve; Heart failure; Regeneration (biology); Neovascularization; Internal medicine; Genetically modified mouse; Endocrinology; Cell growth; Knockout mouse; Transgene; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001552982,0.0005461656,0.0003474995,0.0003020994,0.0001445227,0.0002947207,0.0001961514,0.0004652464,0.004856334],"category_scores_gemma":[0.0001013607,0.0001968726,0.0003764352,0.0001388633,0.0004284018,0.0002601443,0.0002980002,0.0008245289,0.0008981472],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001972702,"about_ca_system_score_gemma":0.0002307728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002670453,"about_ca_topic_score_gemma":0.0003086713,"domain_scores_codex":[0.9998442,0.00001771335,0.0000199407,0.00004501508,0.0000411375,0.0000319924],"domain_scores_gemma":[0.9998744,0.000011583,0.00004556285,0.00001126636,0.000005442516,0.00005172212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002237291,0.00003383182,0.0001502191,0.00006114285,0.000008554236,0.00008866401,0.000008648981,0.00002274057,0.998575,0.00008031214,0.00008448414,0.0006627573],"study_design_scores_gemma":[0.0002102756,0.0009702365,0.01172885,0.0000308234,0.0000569055,0.001494378,0.00005454771,0.0008482386,0.9776683,0.0001327604,0.006791626,0.00001311836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896865,0.002070878,0.003648923,0.0002863223,0.0001539118,0.00006624566,0.001713807,0.0002913314,0.002081814],"genre_scores_gemma":[0.989523,0.001028954,0.002302076,0.0001735822,0.00002921146,0.0001079514,0.001576118,0.00006325665,0.005195749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004856334,"threshold_uncertainty_score":0.01624608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01377917879197671,"score_gpt":0.2825658349013706,"score_spread":0.2687866561093939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}