{"id":"W2790627206","doi":"10.1158/1538-7445.sabcs17-p2-09-18","title":"Abstract P2-09-18: Multiplexed (18-Plex) measurement of protein targets in trastuzumab-treated patients using imaging mass cytometry","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Biosensing Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Fluidigm (Canada)","funders":"","keywords":"Trastuzumab; Mass cytometry; Medicine; Cancer research; Breast cancer; Flow cytometry; Pathology; Cancer; Oncology; Internal medicine; Immunology; Biology; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005395695,0.000137241,0.0001512246,0.0001780637,0.0001244982,0.000017632,0.0002228771,0.00009586578,0.00004593874],"category_scores_gemma":[0.0001466351,0.0001321405,0.00004721641,0.0004343689,0.0002694427,0.000007899845,0.0001150492,0.0001884039,0.000003106916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002649665,"about_ca_system_score_gemma":0.0001721753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005647565,"about_ca_topic_score_gemma":0.0001331099,"domain_scores_codex":[0.998365,0.00007001512,0.0002777466,0.0004116054,0.0004492789,0.0004263269],"domain_scores_gemma":[0.9985315,0.000008693063,0.00009526426,0.0003741014,0.0009122702,0.00007816364],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001225035,0.0001170288,0.008835993,0.00003498043,0.00001417185,0.000001441522,0.00001729334,0.00001284479,0.9851627,0.000004417756,0.0003191982,0.005357477],"study_design_scores_gemma":[0.0005636647,0.0001193014,0.01277069,0.0001344299,0.00000317733,4.346239e-7,0.00003524481,0.0001680944,0.9835025,0.0001011147,0.002460095,0.0001412274],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952678,0.0003930854,0.002964116,0.00005960861,0.00002739279,0.000865509,0.00005318909,0.00001833817,0.0003509583],"genre_scores_gemma":[0.9936591,0.00005159272,0.005929385,0.00001509186,0.000114024,0.000120451,0.00003909173,0.00003097176,0.00004026779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00521625,"threshold_uncertainty_score":0.5388531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1017874141522224,"score_gpt":0.4166769103020577,"score_spread":0.3148894961498353,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}