{"id":"W2790696000","doi":"10.1021/acs.jnatprod.7b00769","title":"Lichen Biosynthetic Gene Clusters. Part I. Genome Sequencing Reveals a Rich Biosynthetic Potential","year":2018,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Polyketide; Biology; Nonribosomal peptide; Polyketide synthase; Secondary metabolism; Lichen; Gene; Gene cluster; Genome; Natural product; Secondary metabolite; Fungus; Biosynthesis; Genetics; Biochemistry; Botany","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008729922,0.0003910465,0.0002708931,0.001187662,0.0002704028,0.0005365238,0.0001564866,0.0001905274,0.003043425],"category_scores_gemma":[0.0001960863,0.000123733,0.000287537,0.001513644,0.0001514478,0.0002173023,0.0003706587,0.0002370835,0.00109557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002422012,"about_ca_system_score_gemma":0.0004373111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003430973,"about_ca_topic_score_gemma":0.004664937,"domain_scores_codex":[0.9998856,0.00000843772,0.000006856645,0.00004763673,0.00002403937,0.00002734802],"domain_scores_gemma":[0.9998583,0.00002534016,0.0000449822,0.0000176133,0.00001663572,0.00003714093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004380561,0.00002940889,0.01008858,0.0005517932,0.00003092584,0.0002435012,0.0002775329,0.0004486667,0.9416055,0.0002064744,0.0007495575,0.0453299],"study_design_scores_gemma":[0.00006472306,0.0004038808,0.6960931,0.0002208812,0.0002557204,0.003060695,0.000851355,0.003903045,0.2176539,0.001185106,0.07623539,0.00007213145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9422019,0.007698146,0.005546943,0.0001730066,0.00002437158,0.00009814555,0.03739707,0.000520593,0.006339875],"genre_scores_gemma":[0.8854687,0.004797636,0.01939851,0.0001629389,0.000026032,0.000129089,0.08271219,0.0001310248,0.007173766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003430973,"threshold_uncertainty_score":0.01018125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01870937926696038,"score_gpt":0.2465982506637754,"score_spread":0.2278888713968151,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}