{"id":"W2790884126","doi":"10.1016/j.canlet.2018.03.030","title":"Immunogenicity and antitumor activity of the superlytic λF7 phage nanoparticles displaying a HER2/neu-derived peptide AE37 in a tumor model of BALB/c mice","year":2018,"lang":"en","type":"article","venue":"Cancer Letters","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Mashhad University of Medical Sciences","keywords":"Immunogenicity; Immune system; Phage display; Peptide; In vivo; Adjuvant; CTL*; In vitro; BALB/c; Biology; HER2/neu; Chemistry; Molecular biology; Immunology; Virology; Cancer; Breast cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001998989,0.0003836127,0.0002246782,0.0002553439,0.0001209769,0.0001774258,0.0001926872,0.0004223675,0.0007861935],"category_scores_gemma":[0.0001434638,0.0001278909,0.0002065833,0.00008573135,0.0002096179,0.0002301233,0.00009740087,0.0005584015,0.0001839438],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001931734,"about_ca_system_score_gemma":0.0001935713,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007940881,"about_ca_topic_score_gemma":0.0005124938,"domain_scores_codex":[0.9998503,0.00001763884,0.000008269951,0.00003238864,0.00003934143,0.00005213443],"domain_scores_gemma":[0.9998547,0.0000337612,0.00002678163,0.00001424007,0.00003147934,0.00003901501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003475485,0.0001077689,0.00007641146,0.00001800969,0.000003400231,0.00002603913,0.00001362142,0.0001378028,0.9985838,0.00005116479,0.00002343771,0.0006109656],"study_design_scores_gemma":[0.00003544042,0.001649077,0.00141825,0.000004290391,0.0000238002,0.0001006568,0.00001534193,0.001581835,0.9947289,0.00003970532,0.0003985334,0.000004247838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99831,0.0002742582,0.0006698766,0.00003429066,0.00002033641,0.00001040222,0.00006184758,0.00002078045,0.0005981653],"genre_scores_gemma":[0.9972741,0.0002369997,0.0005373905,0.00003019462,0.00001239539,0.00001605705,0.0001705085,0.00001071313,0.001711573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007940881,"threshold_uncertainty_score":0.002630055,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02835710121736799,"score_gpt":0.2999149589358397,"score_spread":0.2715578577184717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}