{"id":"W2790884126","doi":"10.1016/j.canlet.2018.03.030","title":"Immunogenicity and antitumor activity of the superlytic λF7 phage nanoparticles displaying a HER2/neu-derived peptide AE37 in a tumor model of BALB/c mice","year":2018,"lang":"en","type":"article","venue":"Cancer Letters","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Mashhad University of Medical Sciences","keywords":"Immunogenicity; Immune system; Phage display; Peptide; In vivo; Adjuvant; CTL*; In vitro; BALB/c; Biology; HER2/neu; Chemistry; Molecular biology; Immunology; Virology; Cancer; Breast cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001671235,0.0001337366,0.0003261822,0.00006122679,0.00007584658,0.000008228467,0.0001523565,0.00002734871,0.0000368593],"category_scores_gemma":[0.00004862625,0.00009230908,0.0000917257,0.0002017421,0.0006811229,0.000095712,0.0001260763,0.0001882272,0.000002145015],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006771336,"about_ca_system_score_gemma":0.0001319533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002539082,"about_ca_topic_score_gemma":0.0004453512,"domain_scores_codex":[0.998911,0.00006554536,0.0002329971,0.0002238766,0.0002707023,0.0002958602],"domain_scores_gemma":[0.9994795,0.00007419958,0.00008872918,0.0002206545,0.00006527214,0.00007164999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007122768,0.00007481359,0.07729069,0.0002639598,0.00004857314,0.00001243139,0.0008481588,0.0000490057,0.9200727,0.00001796984,0.0001217584,0.0004876757],"study_design_scores_gemma":[0.0009203237,0.00009077447,0.2264205,0.0002990286,0.00004077185,0.00001733903,0.00006390948,0.009734498,0.7622784,0.00001381182,0.0000305061,0.00009019973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956273,0.0003699713,0.0000260365,0.003477636,0.00005782909,0.0002935739,0.00004518482,0.000006750977,0.00009573896],"genre_scores_gemma":[0.9984638,0.00007244678,0.0001422107,0.001108237,0.00006106596,0.00002059737,8.750507e-7,0.00001377761,0.0001169664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1577943,"threshold_uncertainty_score":0.383835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02835710121736799,"score_gpt":0.2999149589358397,"score_spread":0.2715578577184717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}