{"id":"W2790887078","doi":"10.1128/aac.02374-17","title":"Short Proline-Rich Lipopeptide Potentiates Minocycline and Rifampin against Multidrug- and Extensively Drug-Resistant Pseudomonas aeruginosa","year":2018,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Manitoba Health Research Council","keywords":"Pseudomonas aeruginosa; Lipopeptide; Antibiotics; Microbiology; Minocycline; Multiple drug resistance; Antimicrobial; Antibacterial activity; Biology; Chemistry; Pharmacology; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001260693,0.0002766238,0.0001688365,0.0001286594,0.00005591259,0.0001324112,0.00009214912,0.0001631929,0.0006245334],"category_scores_gemma":[0.0001532657,0.00007852312,0.0001517099,0.00007994371,0.0001172645,0.0001095516,0.0001347611,0.0002472543,0.0001595402],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006750914,"about_ca_system_score_gemma":0.00009047965,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001419466,"about_ca_topic_score_gemma":0.0003338805,"domain_scores_codex":[0.9999138,0.00002307008,0.0000118744,0.00001033813,0.00002177688,0.00001905019],"domain_scores_gemma":[0.9998974,0.00002105555,0.00003521483,0.000007350871,0.00001348173,0.00002553681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001478282,0.00003565624,0.0001074482,0.00003226715,0.000002760907,0.00003566978,0.00000524131,0.00007427785,0.9985785,0.000006897159,0.000009553673,0.0009637952],"study_design_scores_gemma":[0.00003582956,0.003674622,0.004040953,0.00001077128,0.00002532196,0.0002846701,0.0000244611,0.0005005837,0.990334,0.00001254756,0.001050836,0.000005609355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998555,0.0005192367,0.0004418591,0.00001957503,0.000008974882,0.00002229724,0.00006423496,0.000009277082,0.0003595039],"genre_scores_gemma":[0.9973616,0.0004456821,0.001435461,0.00003132691,0.000009605247,0.00001995868,0.0001510303,0.000004432326,0.0005408417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006245334,"threshold_uncertainty_score":0.002089262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01130704343684137,"score_gpt":0.2376967424887977,"score_spread":0.2263896990519563,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}