{"id":"W2790896335","doi":"10.1111/1462-2920.14089","title":"Genomics‐driven discovery of a novel self‐resistance mechanism in the echinocandin‐producing fungus <i>Pezicula radicicola</i>","year":2018,"lang":"en","type":"article","venue":"Environmental Microbiology","topic":"Fungal Biology and Applications","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"National Natural Science Foundation of China; U.S. Department of Agriculture","keywords":"Echinocandin; Echinocandins; Biology; Fungus; Microbiology; Gene; Fungal protein; Biochemistry; Antifungal; Saccharomyces cerevisiae; Caspofungin; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001238743,0.0002732456,0.0002503586,0.0001841373,0.0001071319,0.0003341559,0.0002158245,0.0003166503,0.0004058109],"category_scores_gemma":[0.0001267994,0.0001299632,0.0003768322,0.0001792307,0.0001464941,0.000153904,0.0002294413,0.0005104554,0.0002287885],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002959599,"about_ca_system_score_gemma":0.000253336,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000763572,"about_ca_topic_score_gemma":0.0007558527,"domain_scores_codex":[0.9999357,0.000006855165,0.000006215017,0.00002238972,0.00001405225,0.00001477925],"domain_scores_gemma":[0.9998974,0.00002094997,0.00003645025,0.00001112065,0.00001322971,0.00002083232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003493715,0.00001064709,0.0002772782,0.00002786913,0.000003446082,0.0000750457,0.00001071956,0.00009964228,0.998212,0.00007670391,0.00001543058,0.001156269],"study_design_scores_gemma":[0.00005956118,0.0005671221,0.06704942,0.00002428972,0.0001234416,0.001925359,0.0001696556,0.005274101,0.9158983,0.0003508549,0.008528369,0.00002942568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916981,0.0004380044,0.005603828,0.0001450535,0.00001191058,0.00005787469,0.0009827724,0.0001248438,0.0009375254],"genre_scores_gemma":[0.9843672,0.0007183622,0.0098815,0.0001112828,0.00001221219,0.00004613019,0.003170223,0.0000541883,0.001638892],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000763572,"threshold_uncertainty_score":0.002147377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006881774456040633,"score_gpt":0.2106517458873226,"score_spread":0.203769971431282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}