{"id":"W2790896335","doi":"10.1111/1462-2920.14089","title":"Genomics‐driven discovery of a novel self‐resistance mechanism in the echinocandin‐producing fungus <i>Pezicula radicicola</i>","year":2018,"lang":"en","type":"article","venue":"Environmental Microbiology","topic":"Fungal Biology and Applications","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Biotechnology Research Institute","funders":"National Natural Science Foundation of China; U.S. Department of Agriculture","keywords":"Echinocandin; Echinocandins; Biology; Fungus; Microbiology; Gene; Fungal protein; Biochemistry; Antifungal; Saccharomyces cerevisiae; Caspofungin; Botany","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001925674,0.0001422857,0.0002428686,0.00005043396,0.00009404916,0.000003737491,0.0001916366,0.0001392326,0.00004946971],"category_scores_gemma":[0.00001019605,0.0001018679,0.00006870794,0.00008408621,0.0004408623,0.0000352291,0.00007649471,0.0002002943,0.00005339872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001124532,"about_ca_system_score_gemma":0.00002507621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001767916,"about_ca_topic_score_gemma":0.00005089885,"domain_scores_codex":[0.9990567,0.00006520445,0.0002606181,0.0003497031,0.0000336871,0.0002340859],"domain_scores_gemma":[0.9994127,0.00007488767,0.0001081257,0.0003750382,0.000003484961,0.00002578616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001098362,0.0004212972,0.007932249,0.00001162446,0.00003929478,0.000004347435,0.0008944196,0.000001376283,0.9891485,0.001173873,0.0002324069,0.00003077226],"study_design_scores_gemma":[0.002937549,0.0007625408,0.08279122,0.00006690634,0.00013867,0.0005179583,0.0007697999,0.00003310999,0.8972817,0.0003526224,0.014044,0.0003039463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997345,0.0003693214,0.000393553,0.0006310006,0.0001028393,0.0005224001,0.0001683061,0.00001354529,0.000454071],"genre_scores_gemma":[0.9958999,0.00007918995,0.002131376,0.001283298,0.000135624,0.00003369043,0.0001473271,0.00001240507,0.0002771651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09186682,"threshold_uncertainty_score":0.4154052,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006881774456040633,"score_gpt":0.2106517458873226,"score_spread":0.203769971431282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}