{"id":"W2790971620","doi":"10.1128/mbio.00358-18","title":"Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses","year":2018,"lang":"en","type":"article","venue":"mBio","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"CIHR Skin Research Training Centre; National Institute of Allergy and Infectious Diseases; National Health and Medical Research Council; Canadian Institutes of Health Research; Canada Research Chairs; Deutsche Forschungsgemeinschaft; National Institutes of Health; International AIDS Vaccine Initiative; Government of Canada; Elizabeth Glaser Pediatric AIDS Foundation; amfAR, The Foundation for AIDS Research","keywords":"Bystander effect; Cytotoxicity; Antibody; Immunology; Human immunodeficiency virus (HIV); Medicine; Virology; Biology; Chemistry; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0007334971,0.0001861692,0.000244699,0.0001004677,0.0002731447,0.00001982518,0.000269258,0.0001358726,0.002477406],"category_scores_gemma":[0.00005224369,0.0001082321,0.0001462028,0.000171502,0.0005707864,0.00003854019,0.00009294032,0.0002073929,0.002544008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001639659,"about_ca_system_score_gemma":0.0001631183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001908703,"about_ca_topic_score_gemma":0.00006030267,"domain_scores_codex":[0.9983764,0.0004883837,0.0002518984,0.0002645943,0.0001597708,0.0004589206],"domain_scores_gemma":[0.9988943,0.0001342314,0.00009693466,0.0005438753,0.0002872088,0.00004346659],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009056713,0.0003066316,0.004384852,0.000006855395,0.0003647446,0.00001514018,0.0003793297,9.11832e-7,0.9806568,0.0000681583,0.01261374,0.0002971343],"study_design_scores_gemma":[0.001353942,0.0007602528,0.02836749,0.00002266713,0.00002775917,0.00001115434,0.0001100562,0.000001170074,0.9474711,0.00003880287,0.02172399,0.0001115472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940793,0.001888776,0.0004706426,0.0001545056,0.000234167,0.0004510031,0.0002970153,0.00004337512,0.002381247],"genre_scores_gemma":[0.9980291,0.0001269108,0.00001697264,0.00001972415,0.00003864086,0.00001226613,0.00008754423,0.00001419741,0.001654647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03318566,"threshold_uncertainty_score":0.9984345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03289653403854394,"score_gpt":0.2907151022989994,"score_spread":0.2578185682604555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}