{"id":"W2790993091","doi":"10.1111/tan.13260","title":"Characterization of a novel allele, <i>HLA‐C*02:135N,</i> by full‐length gene sequencing in a bone marrow donor","year":2018,"lang":"en","type":"article","venue":"HLA","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"","keywords":"Frameshift mutation; Allele; Genetics; Null allele; Gene; Human leukocyte antigen; Biology; HLA-A; Bone marrow transplantation; Molecular biology; Bone marrow; Exon; Immunology; Antigen","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000247447,0.00021988,0.0004069587,0.0001588348,0.0001038234,0.000009160696,0.0002345391,0.0004002613,0.0005623225],"category_scores_gemma":[0.0000411705,0.0002091728,0.00007347611,0.0002314882,0.0003436753,0.0001120753,0.0001130942,0.0002782804,0.0003457915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008703098,"about_ca_system_score_gemma":0.0001053986,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003340741,"about_ca_topic_score_gemma":0.0001517153,"domain_scores_codex":[0.9984978,0.0001272657,0.000498432,0.0003723414,0.00003705334,0.0004671354],"domain_scores_gemma":[0.9992341,0.00005005135,0.0002501378,0.0003415431,0.0001034936,0.00002070822],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002736406,0.0002288875,0.0003144047,0.0000213603,0.00006150818,0.000005336287,0.0006286604,5.87024e-7,0.9956002,0.000149688,0.001223562,0.001492136],"study_design_scores_gemma":[0.00230625,0.0003670011,0.0004298413,0.00003403617,0.00002376736,0.0001342675,0.0001028705,0.00002718001,0.9582193,0.0000217143,0.03810882,0.0002249384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959233,0.001051225,0.0008744615,0.0002435473,0.0005524387,0.0002488928,0.0001046817,0.00005834779,0.0009431092],"genre_scores_gemma":[0.9942173,0.0002520097,0.000268071,0.0003777903,0.00007068298,0.00002791624,0.0005875755,0.00002752966,0.004171143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03738092,"threshold_uncertainty_score":0.8529817,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01310485807099018,"score_gpt":0.2105056911981568,"score_spread":0.1974008331271666,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}