{"id":"W2791146351","doi":"10.1016/j.yfrne.2018.02.001","title":"The effects of chronic stress on the human brain: From neurotoxicity, to vulnerability, to opportunity","year":2018,"lang":"en","type":"review","venue":"Frontiers in Neuroendocrinology","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":370,"is_retracted":false,"has_abstract":false,"ca_institutions":"Douglas Mental Health University Institute; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Hippocampus; Amygdala; Stressor; Chronic stress; Vulnerability (computing); Neuroscience; Neurotoxicity; Psychology; Human brain; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00005685593,0.0007223291,0.001672526,0.0004646277,0.0005155876,0.00009990227,0.00346213,0.0001543267,0.00004422274],"category_scores_gemma":[0.009393583,0.0004456228,0.0004618179,0.0008674388,0.0007823416,0.00004618952,0.00147046,0.0013622,0.00006697224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002289973,"about_ca_system_score_gemma":0.0003029389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001325956,"about_ca_topic_score_gemma":0.0002042453,"domain_scores_codex":[0.9915139,0.004276482,0.001049047,0.001497922,0.0005212755,0.001141373],"domain_scores_gemma":[0.9889187,0.007787755,0.0004999111,0.002444407,0.00004750762,0.0003016821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001750999,0.0003323479,0.0001654203,0.001910985,0.00005577127,0.0008429373,0.00007792301,0.000007752417,0.0006654167,0.001297587,0.06395051,0.9305183],"study_design_scores_gemma":[0.0002829463,0.002312378,0.0005043704,0.001984119,0.00008670013,0.00004374359,0.00001377726,0.00001079201,0.004071846,0.0004938131,0.9897905,0.0004050101],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.04045676,0.9237845,0.0001482954,0.006125537,0.01492418,0.01278497,0.0006800545,0.0002029908,0.0008926975],"genre_scores_gemma":[0.002366757,0.9917091,0.0000124168,0.003407033,0.0003850706,0.001320378,0.000007350816,0.0001118961,0.0006799791],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9301133,"threshold_uncertainty_score":0.9997995,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06368971151258959,"score_gpt":0.346741173053513,"score_spread":0.2830514615409234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}