{"id":"W2791147626","doi":"10.1158/1538-7445.sabcs17-p4-12-05","title":"Abstract P4-12-05: Cost-effectiveness analysis of second-generation multi-gene expression prognostic assays compared with the standard 21-gene recurrence score assay to guide adjuvant therapy decisions in women with early stage breast cancer","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Medicine; Oncology; Breast cancer; Tamoxifen; Internal medicine; Cancer; Gynecology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01147043,0.0011341,0.001644021,0.001069134,0.0003148732,0.0015364,0.001643398,0.001031381,0.00510746],"category_scores_gemma":[0.0236201,0.0006156851,0.002442048,0.00073044,0.0006135151,0.001030214,0.001105968,0.001534024,0.0001939507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00930018,"about_ca_system_score_gemma":0.006345385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0577357,"about_ca_topic_score_gemma":0.02525004,"domain_scores_codex":[0.9958571,0.003212352,0.00009231856,0.0002827748,0.0002656092,0.0002899009],"domain_scores_gemma":[0.9733012,0.02338914,0.001312385,0.0004775074,0.0007574596,0.0007623461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","study_design_scores_codex":[0.01098656,0.0007470086,0.02726571,0.0002490623,0.0008392254,0.00009756622,0.00003741485,0.9306747,0.0005138376,0.003177542,0.00163509,0.02377631],"study_design_scores_gemma":[0.0008796352,0.002362652,0.01022751,0.0000517046,0.0004121698,0.00005151776,0.00004583028,0.9842044,0.0003769046,0.0009121018,0.000442954,0.00003269145],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9654084,0.001561522,0.02014592,0.001900463,0.00008398049,0.001589827,0.004281343,0.0001502923,0.004878295],"genre_scores_gemma":[0.9939856,0.0001804152,0.004185375,0.0001080929,0.00001523409,0.0002477305,0.0007131731,0.00000948562,0.0005547744],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0577357,"threshold_uncertainty_score":0.1147993,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08837461583284571,"score_gpt":0.4003445246708232,"score_spread":0.3119699088379774,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}