{"id":"W2791155737","doi":"10.1200/jco.2018.36.6_suppl.tps390","title":"Intergroup study EORTC-1333-GUCG: A randomized multicenter phase III trial comparing enzalutamide vs. a combination of Ra223 and enzalutamide in asymptomatic or mildly symptomatic castration resistant prostate cancer (CRPC) patients metastatic to bone (PEACE III).","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Enzalutamide; Medicine; Asymptomatic; Prostate cancer; Docetaxel; Internal medicine; Placebo; Clinical endpoint; Cancer; Oncology; Randomized controlled trial; Pathology; Androgen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002079288,0.002452871,0.002072945,0.0005335817,0.0005101252,0.001043724,0.001232109,0.002167684,0.00832732],"category_scores_gemma":[0.00149536,0.0005919805,0.002061246,0.0006993262,0.001091902,0.0007765944,0.0005535898,0.004031633,0.001502957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001578277,"about_ca_system_score_gemma":0.002361748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005122898,"about_ca_topic_score_gemma":0.014405,"domain_scores_codex":[0.9993777,0.00036804,0.00001744975,0.0000842842,0.00005174946,0.0001009038],"domain_scores_gemma":[0.9993844,0.00008578983,0.0001567234,0.00004348517,0.00003754645,0.0002919505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9359258,0.01061364,0.002220616,0.0009025727,0.001710455,0.0001076812,0.0000883977,0.0007734694,0.00455298,0.0004236781,0.01314128,0.02953936],"study_design_scores_gemma":[0.9562998,0.0363217,0.002758082,0.00005856774,0.000677238,0.00006412312,0.00002862648,0.0002591919,0.0003324201,0.0001975067,0.002983154,0.00001962123],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9364059,0.01474309,0.001389262,0.004826864,0.001914635,0.01652822,0.01273716,0.0006840572,0.01077076],"genre_scores_gemma":[0.9334766,0.00681075,0.004026911,0.00932403,0.0008892627,0.01856228,0.01298286,0.0001924743,0.01373489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00832732,"threshold_uncertainty_score":0.02785772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.108548633637985,"score_gpt":0.4911975984817431,"score_spread":0.3826489648437581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}