{"id":"W2791168161","doi":"10.1080/20013078.2018.1432206","title":"Podocyte‐derived microparticles promote proximal tubule fibrotic signaling via p38 MAPK and CD36","year":2018,"lang":"en","type":"article","venue":"Journal of Extracellular Vesicles","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Diabetes Association","keywords":"Podocyte; Cell biology; Fibrosis; Fibronectin; Phosphorylation; CD36; Extracellular matrix; p38 mitogen-activated protein kinases; Scavenger receptor; Signal transduction; MAPK/ERK pathway; Chemistry; Biology; Receptor; Internal medicine; Cancer research; Endocrinology; Kidney; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001256938,0.0002800029,0.0002066992,0.0002330356,0.0001368261,0.0001761153,0.00008009771,0.0002073034,0.001701033],"category_scores_gemma":[0.00008741951,0.000100694,0.0003016838,0.00008027357,0.0001239151,0.000188843,0.0002043751,0.0004488848,0.0003114229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001371024,"about_ca_system_score_gemma":0.0001496785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003155747,"about_ca_topic_score_gemma":0.0004371337,"domain_scores_codex":[0.9998832,0.00002306395,0.000009924627,0.00001654298,0.0000343189,0.00003294888],"domain_scores_gemma":[0.9999375,0.000009237194,0.00001632111,0.000004457313,0.000008561768,0.00002379884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002291587,0.00004885441,0.0001723169,0.00007025065,0.00000452608,0.00008836213,0.00002239319,0.00002010033,0.9978217,0.00005416851,0.00004119611,0.001426927],"study_design_scores_gemma":[0.00005128382,0.0008199607,0.009246737,0.00001002105,0.00002271313,0.0003718389,0.00005758219,0.0008575329,0.9861028,0.0001025772,0.002352841,0.000004270101],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925672,0.0027026,0.002800741,0.0001935384,0.0000361041,0.00004961186,0.0001675757,0.00006876071,0.001413862],"genre_scores_gemma":[0.994352,0.001115691,0.001762372,0.0000549382,0.00002310702,0.00004193372,0.0001665267,0.000005706317,0.002477674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001701033,"threshold_uncertainty_score":0.005690515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379841985522087,"score_gpt":0.2495922738182857,"score_spread":0.2357938539630648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}