{"id":"W2791168161","doi":"10.1080/20013078.2018.1432206","title":"Podocyte‐derived microparticles promote proximal tubule fibrotic signaling via p38 MAPK and CD36","year":2018,"lang":"en","type":"article","venue":"Journal of Extracellular Vesicles","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Diabetes Association","keywords":"Podocyte; Cell biology; Fibrosis; Fibronectin; Phosphorylation; CD36; Extracellular matrix; p38 mitogen-activated protein kinases; Scavenger receptor; Signal transduction; MAPK/ERK pathway; Chemistry; Biology; Receptor; Internal medicine; Cancer research; Endocrinology; Kidney; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004897417,0.0002129955,0.0004490214,0.0001579768,0.0001502387,0.0000876667,0.0001095884,0.00008375543,0.0001646827],"category_scores_gemma":[0.0001397008,0.0001606472,0.0002039807,0.000163389,0.0003047246,0.0002567332,0.00004989327,0.0002386759,0.00003351743],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000354972,"about_ca_system_score_gemma":0.0001134939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008160384,"about_ca_topic_score_gemma":0.00000129573,"domain_scores_codex":[0.9982947,0.00009011566,0.0006659071,0.0002141707,0.0003900544,0.0003450232],"domain_scores_gemma":[0.998661,0.00005470296,0.0003823326,0.0001903248,0.0003415354,0.0003700405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007365166,0.0002452001,0.003580678,0.0002365682,0.0001240716,0.000598575,0.0005051516,0.000003939813,0.9843895,0.00004316769,0.0001718745,0.009364801],"study_design_scores_gemma":[0.001808479,0.002171541,0.03440209,0.0007584352,0.0003826831,0.002110221,0.0003390986,0.0008111307,0.9543784,0.001057275,0.001554448,0.0002262297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800034,0.01760133,0.001154965,0.0007883323,0.0001177465,0.0002527486,0.000003789251,0.00002274269,0.00005497556],"genre_scores_gemma":[0.9897674,0.0001926004,0.008963292,0.0001056662,0.0007463741,0.000002144993,0.00000200816,0.00003464919,0.0001859188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03082141,"threshold_uncertainty_score":0.6551004,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379841985522087,"score_gpt":0.2495922738182857,"score_spread":0.2357938539630648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}