{"id":"W2791179284","doi":"10.1016/j.micinf.2018.03.001","title":"Rapid response to an emerging infectious disease – Lessons learned from development of a synthetic DNA vaccine targeting Zika virus","year":2018,"lang":"en","type":"review","venue":"Microbes and Infection","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Zika virus; Virology; Chikungunya; Flavivirus; Dengue fever; Outbreak; Subclinical infection; Dengue virus; Infectious disease (medical specialty); Virus; Microcephaly; Immunology; Medicine; Biology; Disease; Pediatrics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001235617,0.0004191682,0.0004120264,0.0003800848,0.0001777106,0.0009143518,0.0006631691,0.0009432067,0.00200948],"category_scores_gemma":[0.00165324,0.0001988232,0.0003879964,0.0001843673,0.000800941,0.002028013,0.0006236953,0.003065103,0.0007996385],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006967069,"about_ca_system_score_gemma":0.0006626018,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007216518,"about_ca_topic_score_gemma":0.0007212287,"domain_scores_codex":[0.9996732,0.00007090589,0.00002317588,0.00006269973,0.0001053405,0.00006464231],"domain_scores_gemma":[0.9995217,0.0001471605,0.00004001971,0.0000248434,0.0001620791,0.0001041332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006131884,0.0003361957,0.002478237,0.003873624,0.0001394038,0.0008042204,0.0005106807,0.002515682,0.08378343,0.03262308,0.0428155,0.8295068],"study_design_scores_gemma":[0.0003132891,0.002735313,0.003915101,0.001966564,0.0002020889,0.002049964,0.0006275574,0.004071774,0.05800385,0.02936864,0.896614,0.0001319514],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05360341,0.8306,0.027644,0.064326,0.008087386,0.0001451986,0.0003370159,0.0004103449,0.01484674],"genre_scores_gemma":[0.2704835,0.6776474,0.02155924,0.01737647,0.003858127,0.0001116534,0.0004718055,0.00008719804,0.008404609],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00200948,"threshold_uncertainty_score":0.006722391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04275129233763116,"score_gpt":0.3387103847100285,"score_spread":0.2959590923723973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}