{"id":"W2791179284","doi":"10.1016/j.micinf.2018.03.001","title":"Rapid response to an emerging infectious disease – Lessons learned from development of a synthetic DNA vaccine targeting Zika virus","year":2018,"lang":"en","type":"review","venue":"Microbes and Infection","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Zika virus; Virology; Chikungunya; Flavivirus; Dengue fever; Outbreak; Subclinical infection; Dengue virus; Infectious disease (medical specialty); Virus; Microcephaly; Immunology; Medicine; Biology; Disease; Pediatrics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005661242,0.0004592829,0.001322846,0.0004105419,0.0002565745,0.00006093804,0.00008273692,0.0001927933,0.0003030287],"category_scores_gemma":[0.0003657731,0.0003852033,0.0003541467,0.0003182592,0.00003190026,0.00009762377,0.000118385,0.0002220732,0.00004798796],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001616785,"about_ca_system_score_gemma":0.0004307736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002858622,"about_ca_topic_score_gemma":0.00009187806,"domain_scores_codex":[0.9976393,0.0003402608,0.0007959695,0.000716985,0.0001709245,0.0003365879],"domain_scores_gemma":[0.9984598,0.000117308,0.0003721871,0.0004500627,0.0001577102,0.0004428931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009853365,0.0003374015,0.0001758387,0.003825451,0.0003197106,0.00001261519,0.0002892491,0.00000138528,0.004588458,0.000004113487,0.0003356348,0.9891248],"study_design_scores_gemma":[0.0008970271,0.0004605618,0.002788505,0.008452948,0.002128009,0.00001588581,0.00003038227,0.00003569093,0.0002615789,0.00001608479,0.9844916,0.0004217019],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1896788,0.8082822,0.0004240222,0.000142148,0.0002886077,0.000963363,0.0001042416,0.00009192835,0.00002474556],"genre_scores_gemma":[0.02266097,0.9757267,0.0002272992,0.0001226117,0.0004711589,0.0001807726,0.0004038204,0.00009372144,0.0001129165],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9887031,"threshold_uncertainty_score":0.99986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04275129233763116,"score_gpt":0.3387103847100285,"score_spread":0.2959590923723973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}