{"id":"W2791288749","doi":"10.1016/j.neuropharm.2018.03.020","title":"N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice","year":2018,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Nicotinic Acetylcholine Receptors Study","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Nicotine; Nicotine withdrawal; Pharmacology; Mecamylamine; Conditioned place preference; Agonist; Addiction; Insular cortex; Chemistry; Brain stimulation reward; Craving; Medicine; Antagonist; Psychology; Endocrinology; Receptor; Morphine; Internal medicine; Neuroscience; Nucleus accumbens","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002979045,0.001411667,0.0007504298,0.001166511,0.0004780072,0.0006622734,0.001007863,0.001727241,0.004024643],"category_scores_gemma":[0.0003369098,0.0006193467,0.0007211359,0.0003591767,0.001537481,0.0008816709,0.0005112455,0.002554723,0.0007941861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001006955,"about_ca_system_score_gemma":0.00075062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003497452,"about_ca_topic_score_gemma":0.007947199,"domain_scores_codex":[0.9994797,0.00008095081,0.00004620557,0.0001339724,0.000109962,0.0001491823],"domain_scores_gemma":[0.9992021,0.00007499809,0.0002286315,0.00009089441,0.00005029355,0.0003531671],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002129498,0.0003728482,0.0002412717,0.00003022384,0.00003611302,0.0001028091,0.00003757015,0.00007574528,0.9955734,0.0001483867,0.0001064842,0.001145601],"study_design_scores_gemma":[0.000459747,0.003119107,0.007155088,0.00002698308,0.0001636817,0.0003713503,0.0001758252,0.001323169,0.9847814,0.0003075846,0.002079818,0.00003626921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951794,0.0006184246,0.001285025,0.0006152741,0.0001280648,0.00003663323,0.0007646042,0.0002750709,0.001097544],"genre_scores_gemma":[0.9854167,0.0009088139,0.001515623,0.0004200927,0.00004970879,0.000142417,0.0007340593,0.0002415103,0.0105711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004024643,"threshold_uncertainty_score":0.0134638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007549943169434874,"score_gpt":0.2859528762398568,"score_spread":0.2784029330704219,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}