{"id":"W2791307733","doi":"10.1038/s41419-017-0115-3","title":"BIM and NOXA are mitochondrial effectors of TAF6δ-driven apoptosis","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Université de Sherbrooke; Centre National de la Recherche Scientifique; Sidaction","keywords":"Biology; Effector; Cell biology; Programmed cell death; Transcriptome; Apoptosis; Transcription factor; Mitochondrion; Gene; Gene expression; Mitochondrial DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002079515,0.0003633484,0.0002935908,0.0002864785,0.0002694665,0.0003272996,0.0003119463,0.000295745,0.001152422],"category_scores_gemma":[0.0001310672,0.0001662885,0.0002874375,0.0002208297,0.0002746337,0.00023284,0.000204717,0.0006877374,0.0003733916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004079893,"about_ca_system_score_gemma":0.0002379577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002313994,"about_ca_topic_score_gemma":0.0004433253,"domain_scores_codex":[0.9997231,0.00003069303,0.00002064877,0.00007070894,0.00009842321,0.00005634946],"domain_scores_gemma":[0.999917,0.0000109717,0.00002441009,0.00001041139,0.00001142991,0.00002571626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001409425,0.00002194865,0.0001244603,0.00004977093,0.000003414906,0.00002390154,0.00000794991,0.00004825657,0.9982466,0.0001841475,0.00003673422,0.001112021],"study_design_scores_gemma":[0.00001200005,0.00007981726,0.003127201,0.000004126927,0.000006580342,0.0002076028,0.00001479555,0.0006173544,0.9935108,0.0001189759,0.002297463,0.000003263924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9636039,0.004232407,0.02621368,0.0002877335,0.0001212613,0.0001025241,0.002255504,0.0003893031,0.002793788],"genre_scores_gemma":[0.9722561,0.001860963,0.01788462,0.0001458659,0.00001942097,0.0001881745,0.002483153,0.00005122745,0.005110419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001152422,"threshold_uncertainty_score":0.003855228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007203512837240126,"score_gpt":0.2231447843554699,"score_spread":0.2159412715182298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}