{"id":"W2791307733","doi":"10.1038/s41419-017-0115-3","title":"BIM and NOXA are mitochondrial effectors of TAF6δ-driven apoptosis","year":2018,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Université de Sherbrooke; Centre National de la Recherche Scientifique; Sidaction","keywords":"Biology; Effector; Cell biology; Programmed cell death; Transcriptome; Apoptosis; Transcription factor; Mitochondrion; Gene; Gene expression; Mitochondrial DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00001873286,0.0001037199,0.0001024484,0.00002710506,0.00004892687,0.00001498503,0.00006530921,0.00006118316,0.00002050354],"category_scores_gemma":[0.00004446194,0.00008990186,0.00004957243,0.00002624927,0.0001096105,0.000003322015,0.00007289648,0.00002461968,0.000005547138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001855549,"about_ca_system_score_gemma":0.00003290335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001584784,"about_ca_topic_score_gemma":0.00000536873,"domain_scores_codex":[0.9994673,0.00002229831,0.00009294363,0.0002377515,0.00005353806,0.0001261705],"domain_scores_gemma":[0.9994667,0.000007440763,0.00004677554,0.000173751,0.00005464028,0.0002506949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005981106,0.00009416957,0.1124454,0.0001143074,0.00003209522,0.000003644028,0.00003916385,0.000002156536,0.8810318,0.00002340518,0.004726509,0.0008893394],"study_design_scores_gemma":[0.001444034,0.0009675703,0.05582132,0.00006004651,0.0001357833,0.000001846872,0.00008278053,0.0001733398,0.9366025,0.0001607157,0.004231458,0.0003186559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979059,0.001135776,0.0002051769,0.00003021641,0.000151429,0.0001022271,0.00005395456,0.000004482644,0.0004108504],"genre_scores_gemma":[0.998771,0.0003037929,0.0001679883,0.0001683414,0.0002945171,0.00000855408,0.00003944507,0.000008202622,0.0002382231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05662405,"threshold_uncertainty_score":0.3666092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007203512837240126,"score_gpt":0.2231447843554699,"score_spread":0.2159412715182298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}