{"id":"W2791342378","doi":"10.1177/1534735418757912","title":"Chaga ( <i>Inonotus obliquus</i> ), a Future Potential Medicinal Fungus in Oncology? A Chemical Study and a Comparison of the Cytotoxicity Against Human Lung Adenocarcinoma Cells (A549) and Human Bronchial Epithelial Cells (BEAS-2B)","year":2018,"lang":"en","type":"article","venue":"Integrative Cancer Therapies","topic":"Fungal Biology and Applications","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Université de Caen Normandie","keywords":"Betulinic acid; Inonotus obliquus; Betulin; Cytotoxicity; A549 cell; Chemistry; Traditional medicine; Biology; Medicine; Biochemistry; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000237051,0.0003078721,0.0006981702,0.0000981895,0.0003076641,0.00001464858,0.0002118349,0.0002556362,0.00007294335],"category_scores_gemma":[0.00001385157,0.0001891482,0.00008943749,0.0002210539,0.001416555,0.00005036632,0.0001171864,0.0007291282,0.000001359706],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001598585,"about_ca_system_score_gemma":0.0001571712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006822932,"about_ca_topic_score_gemma":0.002266692,"domain_scores_codex":[0.9983124,0.0002541525,0.0004740806,0.0004686567,0.0002029061,0.0002878296],"domain_scores_gemma":[0.9990865,0.00009617912,0.0002521201,0.0002739907,0.0001845192,0.000106702],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007446469,0.0006364971,0.1155745,0.0000293778,0.0001986172,0.00000677908,0.02362374,3.121147e-7,0.856739,0.0002289443,0.0004078015,0.001809789],"study_design_scores_gemma":[0.004858226,0.002733201,0.2922136,0.0001977028,0.0001951199,0.00001411794,0.01839731,0.00007881744,0.6800708,0.0002238532,0.0007631626,0.0002541879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933589,0.003355847,0.00002175111,0.001314703,0.0002726075,0.001288284,0.0001242801,0.00002355161,0.0002401147],"genre_scores_gemma":[0.9978905,0.0001330234,0.00006412083,0.0006460018,0.0009810627,0.0001927536,0.00001306766,0.00001882745,0.00006063924],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1766682,"threshold_uncertainty_score":0.771324,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.016262045356406,"score_gpt":0.3344887174313049,"score_spread":0.3182266720748989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}