{"id":"W2791424999","doi":"10.1111/trf.14532","title":"Apheresis buffy coat collection without photoactivation has no effect on apoptosis, cell proliferation, and total viability of mononuclear cells collected using photopheresis systems","year":2018,"lang":"en","type":"article","venue":"Transfusion","topic":"Cutaneous lymphoproliferative disorders research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals; Dartmouth College; Therakos","keywords":"Extracorporeal Photopheresis; Buffy coat; Propidium iodide; Photopheresis; Methoxsalen; Peripheral blood mononuclear cell; Viability assay; Apoptosis; Annexin; Medicine; Andrology; Immunology; Molecular biology; Flow cytometry; Chemistry; Programmed cell death; Biology; Transplantation; Biochemistry; In vitro; Surgery; Graft-versus-host disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004540515,0.0003187491,0.0006226646,0.0002815299,0.0005643558,0.00008175125,0.00006891672,0.0002608833,0.0003268002],"category_scores_gemma":[0.0001682685,0.0002787867,0.0001119952,0.0008214067,0.0003139756,0.0001250373,0.0000217641,0.0002231751,0.00002210412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003812347,"about_ca_system_score_gemma":0.0003016701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002605859,"about_ca_topic_score_gemma":0.0002090498,"domain_scores_codex":[0.9973774,0.000494589,0.0005014735,0.000601868,0.0006897526,0.0003348985],"domain_scores_gemma":[0.9981817,0.0002463062,0.0001502775,0.0003634561,0.0008909354,0.0001673348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01135024,0.0005992253,0.01853573,0.0009649734,0.00007101092,0.000001970612,0.001181706,0.0001074265,0.966604,0.00000216007,0.0003564545,0.000225128],"study_design_scores_gemma":[0.004402063,0.006076572,0.003320381,0.0002483363,0.0001552046,0.00004763493,0.0002422282,0.03719636,0.9480023,0.000004721439,0.00007062723,0.000233511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920227,0.0000426445,0.00110285,0.00005062166,0.0002155508,0.00457646,0.0000246079,0.00008520272,0.001879368],"genre_scores_gemma":[0.9983158,0.00005777276,0.0003621219,0.00003093,0.0001276824,0.00009916053,0.00002292158,0.00006274746,0.0009208802],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03708893,"threshold_uncertainty_score":0.9999664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01845138818107462,"score_gpt":0.2699176128767646,"score_spread":0.25146622469569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}