{"id":"W2791424999","doi":"10.1111/trf.14532","title":"Apheresis buffy coat collection without photoactivation has no effect on apoptosis, cell proliferation, and total viability of mononuclear cells collected using photopheresis systems","year":2018,"lang":"en","type":"article","venue":"Transfusion","topic":"Cutaneous lymphoproliferative disorders research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals; Dartmouth College; Therakos","keywords":"Extracorporeal Photopheresis; Buffy coat; Propidium iodide; Photopheresis; Methoxsalen; Peripheral blood mononuclear cell; Viability assay; Apoptosis; Annexin; Medicine; Andrology; Immunology; Molecular biology; Flow cytometry; Chemistry; Programmed cell death; Biology; Transplantation; Biochemistry; In vitro; Surgery; Graft-versus-host disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007356577,0.0003688425,0.0004885317,0.0002128938,0.0002378499,0.0005147902,0.0002355844,0.0003425247,0.001791828],"category_scores_gemma":[0.0006731068,0.0001471448,0.000217605,0.0001632283,0.0002238908,0.000197701,0.0002203923,0.0005825135,0.0003087617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002072249,"about_ca_system_score_gemma":0.0002699801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004225832,"about_ca_topic_score_gemma":0.0004655917,"domain_scores_codex":[0.9991623,0.0002144317,0.00006359655,0.00018728,0.0002806485,0.00009176489],"domain_scores_gemma":[0.9994658,0.0001607145,0.0001206833,0.00009251121,0.00006806624,0.00009228967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.05195051,0.006138871,0.006973776,0.0003207303,0.0002020343,0.0001101869,0.0001847791,0.000161728,0.901261,0.00004278134,0.0002893257,0.0323644],"study_design_scores_gemma":[0.0053996,0.2138574,0.1089092,0.000063984,0.0004671619,0.001198037,0.0001293752,0.00173219,0.6628515,0.00007612119,0.005286257,0.00002915182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985502,0.0007194447,0.0003602279,0.000012401,0.00001766099,0.00005528714,0.00004152042,0.000009466031,0.0002337867],"genre_scores_gemma":[0.997843,0.000322075,0.0007650479,0.00005232789,0.000028652,0.00008614996,0.000303125,0.000007679026,0.0005918957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001791828,"threshold_uncertainty_score":0.00599426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01845138818107462,"score_gpt":0.2699176128767646,"score_spread":0.25146622469569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}