{"id":"W2791452970","doi":"10.1016/j.cryobiol.2017.10.101","title":"Optimization of additives to mitigate chondrocyte toxicity during exposure to cryoprotective agents","year":2018,"lang":"en","type":"article","venue":"Cryobiology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Toxicity; Chemistry; Chondrocyte; Toxicology; Pharmacology; Biology; Biochemistry; In vitro; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002635857,0.000475736,0.000334795,0.0003298105,0.0001985657,0.0004839454,0.000289612,0.0002851515,0.00108254],"category_scores_gemma":[0.0005969353,0.0001401023,0.000301326,0.0002011652,0.0001770518,0.0003053277,0.000215201,0.0003668511,0.0003083883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002133047,"about_ca_system_score_gemma":0.0004213676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00112312,"about_ca_topic_score_gemma":0.002172016,"domain_scores_codex":[0.9997559,0.00003628684,0.00003249262,0.00005167936,0.00007742418,0.00004608585],"domain_scores_gemma":[0.9997439,0.00003977346,0.00007135843,0.00001632522,0.00009808988,0.00003057741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002213277,0.00009312802,0.0002910738,0.0001399837,0.00001333791,0.00002967633,0.00002286664,0.0003240101,0.9949306,0.00006552475,0.00007315588,0.003795413],"study_design_scores_gemma":[0.000009024052,0.0005109701,0.001401691,0.00002532812,0.00005402589,0.00004534635,0.00003932882,0.0006352394,0.9942297,0.000032673,0.003007974,0.000008800471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804626,0.004679202,0.01170381,0.0001286425,0.0001575471,0.0001694712,0.0003040787,0.0001390947,0.002255503],"genre_scores_gemma":[0.9770329,0.003590627,0.01620086,0.0001022605,0.00003576263,0.0001261421,0.0003487269,0.00006723795,0.002495546],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00112312,"threshold_uncertainty_score":0.003621459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01349017567955935,"score_gpt":0.2640085413159894,"score_spread":0.2505183656364301,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}