{"id":"W2791527077","doi":"10.1007/s10689-018-0076-4","title":"A retrospective review of 48 individuals, including 12 families, molecularly diagnosed with hereditary leiomyomatosis and renal cell cancer (HLRCC)","year":2018,"lang":"en","type":"review","venue":"Familial Cancer","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Children's Hospital of Eastern Ontario","funders":"","keywords":"Leiomyomatosis; Medicine; Germline mutation; Germline; Pathology; Genetic testing; Papillary renal cell carcinomas; Renal cell carcinoma; Oncology; Internal medicine; Mutation; Leiomyoma; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004033062,0.001123042,0.004460776,0.0003842263,0.0001381498,0.00002755652,0.0003264283,0.0004774285,0.0003411919],"category_scores_gemma":[0.00009366163,0.0007858435,0.0006725505,0.0008701952,0.0004368061,0.0001358115,0.0002930183,0.0007364932,0.00002017609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001731804,"about_ca_system_score_gemma":0.002288289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005655546,"about_ca_topic_score_gemma":0.0006586231,"domain_scores_codex":[0.9952875,0.0002883161,0.001241994,0.001275189,0.001249591,0.0006573989],"domain_scores_gemma":[0.9969256,0.0001265547,0.001132018,0.000918926,0.0005089585,0.0003879245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003765823,0.0005370368,0.01156809,0.5832333,0.005109064,0.001569764,0.0008384065,6.762468e-7,0.00006453862,0.00001507662,0.05300554,0.343682],"study_design_scores_gemma":[0.001997377,0.001255761,0.003201739,0.3551701,0.01282318,0.0001673309,0.00005486705,0.000001468667,0.0002161422,0.000005717454,0.6242361,0.0008702048],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002081072,0.9902047,0.00001096148,0.00006725988,0.0004622408,0.003622802,0.001354812,0.00006598022,0.00213019],"genre_scores_gemma":[0.0005070463,0.9941182,0.0006333882,0.0004712697,0.001003725,0.002122809,0.0003984708,0.0002153691,0.0005296943],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5712306,"threshold_uncertainty_score":0.9994593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04536527443222436,"score_gpt":0.3220327230599673,"score_spread":0.2766674486277429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}