{"id":"W2791534718","doi":"10.21037/aes.2018.ab012","title":"AB012. Retinopathy in a mouse model for Zellweger spectrum disorder","year":2018,"lang":"en","type":"article","venue":"Annals of Eye Science","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University","funders":"","keywords":"Zellweger syndrome; Retina; Retinal; Peroxisomal disorder; Biology; Visual acuity; Internal medicine; Medicine; Endocrinology; Pathology; Ophthalmology; Receptor; Peroxisome; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005180746,0.001382181,0.0004627868,0.002583429,0.0006684315,0.0006014325,0.0007517722,0.001854705,0.01123738],"category_scores_gemma":[0.0002105716,0.0005018878,0.0007784167,0.0007404467,0.0006938097,0.0006593427,0.0004999881,0.001839079,0.003741913],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000739171,"about_ca_system_score_gemma":0.0004787619,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001654415,"about_ca_topic_score_gemma":0.001966173,"domain_scores_codex":[0.9992731,0.0001075778,0.00009501379,0.0002176647,0.0001994316,0.0001071726],"domain_scores_gemma":[0.9995665,0.00004258959,0.0001652706,0.0000484861,0.00003645237,0.0001407229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000883708,0.0004407156,0.0004654356,0.000104906,0.00002391852,0.0005836847,0.00006333538,0.000108779,0.9927463,0.0006763309,0.0007076898,0.003195196],"study_design_scores_gemma":[0.001230991,0.005988312,0.02082111,0.0003676372,0.0002923681,0.008018158,0.0003387938,0.004256449,0.9106928,0.001213119,0.04669121,0.00008905327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9497321,0.004841963,0.01189657,0.001625195,0.0004288118,0.0006518936,0.01162592,0.003095991,0.01610154],"genre_scores_gemma":[0.9157555,0.004259397,0.02080695,0.001163924,0.0001111303,0.001907003,0.01051422,0.0007779112,0.04470387],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01123738,"threshold_uncertainty_score":0.03759277,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03011841741624142,"score_gpt":0.3301533007789341,"score_spread":0.3000348833626926,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}