{"id":"W2791544907","doi":"10.1200/jco.2018.36.4_suppl.211","title":"Genomics-driven precision medicine for advanced pancreatic ductal carcinoma (PDAC): Early results from the COMPASS trial (NCT02750657).","year":2018,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; Ontario Institute for Cancer Research; Toronto General Hospital; University Health Network; BC Cancer Agency; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Oncology; Precision medicine; Internal medicine; Primary tumor; Cancer; Pathology; Metastasis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001621904,0.0004480166,0.0004816729,0.0001811381,0.0001434045,0.0006563944,0.0002497742,0.0004397446,0.004014451],"category_scores_gemma":[0.001000883,0.00008748798,0.0006168928,0.0003259332,0.0003533844,0.0003009272,0.0004080258,0.0008843615,0.0003734487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007066191,"about_ca_system_score_gemma":0.0007240411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007036958,"about_ca_topic_score_gemma":0.002029149,"domain_scores_codex":[0.9995726,0.0002671909,0.000009978232,0.00004942752,0.00005539269,0.00004542902],"domain_scores_gemma":[0.9995207,0.0001586023,0.0001050634,0.00003541079,0.00004309096,0.0001370796],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3722438,0.006118328,0.05345859,0.002622666,0.003871132,0.000711262,0.0003077548,0.00440864,0.02385066,0.002746337,0.03845878,0.4912021],"study_design_scores_gemma":[0.3816346,0.2296245,0.2340306,0.00137544,0.005044736,0.00281063,0.0004175733,0.006259162,0.0195434,0.004225974,0.1149058,0.0001275782],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9511509,0.02880492,0.001635421,0.004688824,0.0003388154,0.0006417538,0.003373727,0.000135086,0.009230494],"genre_scores_gemma":[0.9777122,0.006685027,0.00274548,0.003597997,0.0003720766,0.0004954031,0.005488812,0.00002765158,0.002875482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004014451,"threshold_uncertainty_score":0.0134297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08227963421941238,"score_gpt":0.4189014470934742,"score_spread":0.3366218128740618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}