{"id":"W2791668997","doi":"10.1016/j.bpj.2017.11.3231","title":"Global Dimensions are Decoupled from Electrostatics in the Intrinsically Disordered Protein Sic1","year":2018,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Intrinsically disordered proteins; Radius of gyration; Conformational ensembles; Sequence (biology); Biophysics; Electrostatics; Chemistry; Protein structure; Physics; Biology; Polymer; Biochemistry; Nuclear magnetic resonance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001495451,0.0002075209,0.0002931545,0.0001373562,0.0003741295,0.0004911038,0.0003127994,0.0002433528,0.001042258],"category_scores_gemma":[0.0002984805,0.0002461516,0.0001479509,0.0001130029,0.0006854577,0.000516139,0.0003559418,0.0005169676,0.0001505846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002774056,"about_ca_system_score_gemma":0.0002325735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000591904,"about_ca_topic_score_gemma":0.0009502184,"domain_scores_codex":[0.999949,0.00000590234,0.000003030402,0.00001184419,0.00001646637,0.00001383415],"domain_scores_gemma":[0.999854,0.00003779544,0.00003059734,0.00001160058,0.0000189042,0.00004701319],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009407678,0.0001971522,0.009201949,0.0003439406,0.00009778982,0.0006188691,0.0004624677,0.02991762,0.906561,0.03507486,0.001622182,0.01496143],"study_design_scores_gemma":[0.0004227661,0.0006533867,0.1012599,0.00005025346,0.0001515903,0.001315582,0.0008846221,0.531259,0.291775,0.06668794,0.00524511,0.000294888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948241,0.00020355,0.003342792,0.0001344996,0.00002091761,0.000003048216,0.00002924754,0.00005863978,0.001383225],"genre_scores_gemma":[0.9993764,0.00005703692,0.0002953678,0.00002108244,0.000004633207,0.000001949375,0.00002810487,0.00001551522,0.0002000227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001042258,"threshold_uncertainty_score":0.003486633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005881389715414872,"score_gpt":0.243424530439882,"score_spread":0.2375431407244671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}