{"id":"W2791727878","doi":"10.1002/smtd.201700319","title":"DNAzymes: Selected for Applications","year":2018,"lang":"en","type":"article","venue":"Small Methods","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Deoxyribozyme; DNA; Biosensor; Computational biology; Analyte; Rolling circle replication; Chemistry; Biology; Nanotechnology; Biochemistry; DNA polymerase; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003456744,0.00009876635,0.0001069272,0.00003499562,0.0001130965,0.00001204673,0.0001256629,0.0001189145,0.000001796216],"category_scores_gemma":[0.0001847006,0.00008560203,0.00007646391,0.0001915791,0.0001037427,9.081866e-7,0.00003994255,0.00003639122,0.000002209149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006996309,"about_ca_system_score_gemma":0.00003315461,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002559147,"about_ca_topic_score_gemma":0.00002140055,"domain_scores_codex":[0.9992989,0.00007869739,0.0001299729,0.0002905615,0.000031278,0.0001706182],"domain_scores_gemma":[0.9992556,0.00002886435,0.00005903871,0.0003116002,0.0003011047,0.00004377412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002447497,0.00001954134,0.00006518693,0.000005191036,0.00003373312,3.955208e-8,0.00000475164,1.402074e-7,0.9166201,0.0001806783,0.0009012689,0.08214486],"study_design_scores_gemma":[0.00007970056,0.000167119,0.00008342336,0.000002045992,0.00002328113,0.000002745379,0.000009613747,0.00005821416,0.7181258,0.0008242205,0.2805305,0.0000933621],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.01360614,0.0001351082,0.9848658,0.00009645792,0.00003782689,0.0002681677,0.00001303214,0.00006882946,0.0009085679],"genre_scores_gemma":[0.1135968,0.00003014147,0.8844136,0.0002661373,0.0005596224,0.0001083343,0.00008995981,0.00001672683,0.0009186235],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.2796293,"threshold_uncertainty_score":0.3490749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02958606817257635,"score_gpt":0.3997283678132934,"score_spread":0.370142299640717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}