{"id":"W2791770850","doi":"10.1038/nm.4501","title":"Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia","year":2018,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Ion Channels and Receptors","field":"Neuroscience","cited_by":418,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Complementary and Integrative Health; National Heart, Lung, and Blood Institute","keywords":"Nociceptor; TRPV1; Pneumonia; Immunology; Calcitonin gene-related peptide; Bronchoconstriction; Lung; Medicine; Nociception; Neuropeptide; Biology; Receptor; Asthma; Internal medicine; Transient receptor potential channel","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001955908,0.0001886264,0.0002343818,0.0002357413,0.0002170081,0.00002671577,0.0001047958,0.0002683965,0.0002049362],"category_scores_gemma":[0.0006744939,0.0001388652,0.00002207612,0.0002816833,0.0006650966,0.0001200171,0.00009145664,0.0007311854,0.000007679757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002154817,"about_ca_system_score_gemma":0.00002946589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004732548,"about_ca_topic_score_gemma":0.00004284443,"domain_scores_codex":[0.998584,0.000251806,0.0002036867,0.0004531728,0.0002207899,0.0002865501],"domain_scores_gemma":[0.9991204,0.0004774489,0.00006737592,0.0001414148,0.00004659053,0.0001468187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001658509,0.00004874926,0.0006378532,0.000028528,0.000001841373,0.00004144721,0.0009919736,7.957537e-7,0.9960231,0.00005798206,0.001792282,0.0002095647],"study_design_scores_gemma":[0.003927657,0.001471612,0.03569708,0.0001532798,0.00005701572,0.0004393252,0.0002882824,0.0005722514,0.9083135,0.00008118703,0.0485627,0.0004361614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903306,0.0003018112,0.000003245318,0.004056795,0.003962223,0.0002121398,0.00002642119,0.00004797416,0.001058775],"genre_scores_gemma":[0.9956178,0.0002935366,0.00001752538,0.0009109069,0.001964336,0.00000707728,0.000003226764,0.00002201874,0.001163593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08770969,"threshold_uncertainty_score":0.5662757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01417636208293781,"score_gpt":0.2864790926952119,"score_spread":0.2723027306122741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}