{"id":"W2791883352","doi":"10.1016/j.leukres.2018.02.012","title":"AML refractory to primary induction with Ida-FLAG has a poor clinical outcome","year":2018,"lang":"en","type":"article","venue":"Leukemia Research","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research; Ontario Ministry of Health and Long-Term Care; Princess Margaret Cancer Foundation","keywords":"Flag (linear algebra); Refractory (planetary science); Medicine; Complete remission; Internal medicine; Induction chemotherapy; Oncology; Chemotherapy; Salvage therapy; Transplantation; Surgery; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.007360641,0.0003826235,0.0008623847,0.001182758,0.0006624739,0.0002073374,0.0008109388,0.0006228591,0.0008540507],"category_scores_gemma":[0.003131387,0.0002882991,0.0001900523,0.00244095,0.00220995,0.0003375673,0.0008064801,0.004346904,0.006427238],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.007095864,"about_ca_system_score_gemma":0.007826228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001072455,"about_ca_topic_score_gemma":0.0002382914,"domain_scores_codex":[0.9917058,0.0009241771,0.0009915087,0.001348345,0.003199762,0.001830457],"domain_scores_gemma":[0.9934766,0.0009493189,0.0001182823,0.0017778,0.002182607,0.001495336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02380802,0.001193292,0.1559483,0.0007035428,0.0006480713,0.002225121,0.001814404,0.000007168908,0.06361833,0.0006308641,0.5847461,0.1646568],"study_design_scores_gemma":[0.01004602,0.01431067,0.3438719,0.0004405993,0.00009072285,0.0005855665,0.0008502709,0.0004916556,0.006971584,0.0001861089,0.6214489,0.0007059809],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9498978,0.00009200782,0.0003127399,0.01550553,0.0003339697,0.001997029,0.00001253567,0.0002395863,0.03160878],"genre_scores_gemma":[0.9545179,0.00008779158,0.006814702,0.003790329,0.004191318,0.0002426457,0.00006006391,0.0001731436,0.03012208],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1879236,"threshold_uncertainty_score":0.9999569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2133251517237102,"score_gpt":0.4632169772252464,"score_spread":0.2498918255015362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}