{"id":"W2791887519","doi":"10.1128/jvi.00441-18","title":"Central Role of the NF-κB Pathway in the <i>Scgb1a1</i> -Expressing Epithelium in Mediating Respiratory Syncytial Virus-Induced Airway Inflammation","year":2018,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Respiratory viral infections research","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; University of British Columbia; National Science Foundation","keywords":"Biology; Histone acetyltransferase; Inflammation; Interferon regulatory factors; Respiratory epithelium; IRF1; Cancer research; Molecular biology; Immunology; Transcription factor; Innate immune system; Immune system; Epithelium; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001722113,0.0003643653,0.0001958154,0.0002491123,0.0002000343,0.0003667552,0.0002131886,0.0003876884,0.001688173],"category_scores_gemma":[0.00009613312,0.00016133,0.000326205,0.00007020491,0.0004073564,0.0002159006,0.000240244,0.0007067763,0.0006075088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003451672,"about_ca_system_score_gemma":0.000210251,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006605994,"about_ca_topic_score_gemma":0.0005783797,"domain_scores_codex":[0.9998286,0.00002445185,0.00001414583,0.00003847032,0.00004023819,0.00005396417],"domain_scores_gemma":[0.9998052,0.00001358556,0.00006327799,0.00002112488,0.00002340346,0.00007351326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004150679,0.00000499837,0.0001409444,0.0000183764,0.000001401831,0.00003105529,0.000004547142,0.000009677884,0.9995504,0.00003827648,0.00001363428,0.0001452404],"study_design_scores_gemma":[0.00002767188,0.0002153431,0.01677815,0.00002813686,0.00001845075,0.0008723348,0.0001097494,0.0007092975,0.97868,0.0001243568,0.002431231,0.000005292752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934243,0.002058004,0.0025201,0.0002151934,0.00004399154,0.00002276291,0.0003892992,0.0001244812,0.001201868],"genre_scores_gemma":[0.995987,0.0005425893,0.001053022,0.00007440639,0.00001092929,0.00002400887,0.0003857912,0.0000247618,0.00189757],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001688173,"threshold_uncertainty_score":0.00564754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0293205012858524,"score_gpt":0.3250072710136657,"score_spread":0.2956867697278133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}