{"id":"W2791888954","doi":"10.1056/nejmoa1710922","title":"Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa","year":2018,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Fungal Infections and Studies","field":"Medicine","cited_by":405,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; National Institutes of Health; Agence Nationale de Recherches sur le Sida et les Hépatites Virales; Center for AIDS Research, University of Washington; National Institute for Health and Care Research; Wellcome Trust","keywords":"Cryptococcal meningitis; Antifungal; Cryptococcosis; Cryptococcus neoformans; Meningitis; Medicine; Microbiology; Biology; Virology; Immunology; Human immunodeficiency virus (HIV); Pediatrics; Viral disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007175725,0.0003811126,0.0009457822,0.0005834989,0.0002934791,0.0002307748,0.0003704992,0.0003500491,0.003352749],"category_scores_gemma":[0.0008959481,0.0001309698,0.0003612896,0.0004336011,0.0002848852,0.0001666431,0.000337089,0.0005906594,0.0004087396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002905415,"about_ca_system_score_gemma":0.0004166275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002743492,"about_ca_topic_score_gemma":0.0006458976,"domain_scores_codex":[0.9995987,0.0002116877,0.0000467016,0.00003747518,0.00006457377,0.00004092731],"domain_scores_gemma":[0.9996898,0.00009084465,0.0001131041,0.00001515005,0.00001898458,0.00007214949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0810079,0.005135323,0.01435557,0.00596833,0.001309732,0.001628307,0.0002132886,0.003162404,0.02135771,0.001221213,0.006569889,0.8580703],"study_design_scores_gemma":[0.2890507,0.3443779,0.09639806,0.004876202,0.005288571,0.02166472,0.0003999703,0.005230298,0.02201223,0.005494342,0.2050087,0.0001983105],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8333859,0.1545893,0.001745569,0.001723039,0.000581248,0.002091378,0.0004171297,0.00009787148,0.005368508],"genre_scores_gemma":[0.9571332,0.03506358,0.004534381,0.0004854931,0.0003348192,0.001235701,0.0001915278,0.000008609942,0.001012703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003352749,"threshold_uncertainty_score":0.0112161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05798650243405418,"score_gpt":0.3376288505914131,"score_spread":0.2796423481573589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}