{"id":"W2792059589","doi":"10.1093/jcag/gwy008.196","title":"A195 GLUTAMINE SYNTHETASE IN ENDOTHELIAL CELLS OF THE BLOOD-BRAIN BARRIER: NEW TARGET FOR THE TREATMENT OF HEPATIC ENCEPHALOPATHY?","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Hyperammonemia; Glutamine synthetase; Hepatic encephalopathy; Western blot; Glutamine; Blood–brain barrier; Internal medicine; Endocrinology; Glutamate receptor; Biology; Chemistry; Medicine; Biochemistry; Central nervous system; Amino acid; Cirrhosis; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003031367,0.0003797221,0.0009949816,0.0003899842,0.0001508334,0.000698067,0.0004972559,0.0008256835,0.001950201],"category_scores_gemma":[0.0001749337,0.000121445,0.0004782293,0.0003343627,0.000324156,0.0007393919,0.0003107506,0.001887919,0.0005535046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002773119,"about_ca_system_score_gemma":0.0003283222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003328171,"about_ca_topic_score_gemma":0.0009245507,"domain_scores_codex":[0.9998995,0.00002338171,0.000009818906,0.00001843496,0.00002061057,0.00002828248],"domain_scores_gemma":[0.9999111,0.00001094181,0.00002245828,0.000006830251,0.00002773355,0.00002091355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003858811,0.001611498,0.002068171,0.008389575,0.000538633,0.002009733,0.0001827679,0.0006616742,0.2483048,0.005613619,0.02457866,0.7021821],"study_design_scores_gemma":[0.003752574,0.01679828,0.01661851,0.00225785,0.001921439,0.009725322,0.0005970196,0.003923074,0.1454071,0.009142322,0.7896749,0.0001815983],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.05672317,0.921721,0.006895264,0.009265757,0.001538819,0.000124365,0.0002319762,0.0002649964,0.003234548],"genre_scores_gemma":[0.2656022,0.710231,0.008221618,0.005569929,0.001804594,0.0002836915,0.0007580421,0.00004834918,0.007480526],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001950201,"threshold_uncertainty_score":0.006524086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004482486374683947,"score_gpt":0.2080146489587497,"score_spread":0.2035321625840657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}