{"id":"W2792093419","doi":"10.1093/jcag/gwy008.171","title":"A170 MACROPHAGE SUBSET PHENOTYPE IS ALTERED IN CHRONIC HCV INFECTION & MAY CONTRIBUTE TO GENERALIZED CD8+T-CELL DYSFUNCTION","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; Children's Hospital of Eastern Ontario; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario HIV Treatment Network","keywords":"CD8; CD163; Immunology; Phenotype; Cytotoxic T cell; Chronic infection; T cell; CD86; Biology; Immune system; Medicine; In vitro; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001201488,0.0001680141,0.000171445,0.0002451205,0.0001642265,0.0002382649,0.00006077826,0.0001854016,0.001050273],"category_scores_gemma":[0.0001496127,0.00009986354,0.0001203388,0.0001248513,0.000155553,0.0001236664,0.0001829405,0.0002103398,0.0002544389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008935598,"about_ca_system_score_gemma":0.00008710522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002819569,"about_ca_topic_score_gemma":0.0003279036,"domain_scores_codex":[0.9999063,0.00001959044,0.00001295016,0.00002029248,0.00001481258,0.00002605954],"domain_scores_gemma":[0.9999133,0.000009797453,0.00003479463,0.000009390936,0.00001327704,0.00001948759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001879638,0.00008960976,0.104368,0.0001423103,0.00002791471,0.00118323,0.0002056311,0.0001058936,0.8809406,0.0001729703,0.0001674646,0.01071671],"study_design_scores_gemma":[0.00008038562,0.001611344,0.8343317,0.00007018276,0.00009229819,0.009107299,0.001053118,0.001234788,0.1469035,0.0006512536,0.004841523,0.00002263429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998378,0.0005748173,0.0004163029,0.00003649201,0.000005141804,0.00001268269,0.0001033454,0.000008196341,0.0004650384],"genre_scores_gemma":[0.9987142,0.0002769614,0.0003483429,0.00004055764,0.000008217794,0.00002036426,0.0001193368,0.000003748931,0.00046823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001050273,"threshold_uncertainty_score":0.003513455,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008951051500006493,"score_gpt":0.234610399157397,"score_spread":0.2256593476573905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}