{"id":"W2792155406","doi":"","title":"The cooperation of the tumor suppressor gene Dlc1 and the oncogene Kras in tumorigenesis","year":2012,"lang":"en","type":"article","venue":"Mspace (University of Manitoba)","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Manitoba Health Research Council","keywords":"KRAS; Carcinogenesis; Tumor suppressor gene; Oncogene; Gene; Suppressor; Cancer research; Mutation; Biology; Genetics; Cell cycle","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002161812,0.0003715576,0.0002281218,0.0003943737,0.0002341128,0.0003339384,0.0002276679,0.0003056588,0.0007291954],"category_scores_gemma":[0.0001486742,0.0001312411,0.0001108416,0.0001907697,0.0002990407,0.0002391798,0.0002566088,0.0003502285,0.0002032594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006014718,"about_ca_system_score_gemma":0.000509629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001342343,"about_ca_topic_score_gemma":0.00234226,"domain_scores_codex":[0.9998673,0.0000230058,0.000006000278,0.00002391073,0.00004010279,0.00003971928],"domain_scores_gemma":[0.9998685,0.00003304216,0.00003342337,0.00001014976,0.00001918554,0.00003570407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000379034,0.00004915959,0.005384948,0.00007992832,0.000008546624,0.0003920796,0.00006354963,0.0004895101,0.9863668,0.001164125,0.00007285138,0.005549307],"study_design_scores_gemma":[0.00003434093,0.0005117515,0.03368866,0.00002308743,0.00004631292,0.001240477,0.0002009004,0.00278164,0.9544302,0.0003788382,0.00665112,0.00001266936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936335,0.003507207,0.001196956,0.0001999503,0.000008221902,0.00001281919,0.00008004531,0.00001440638,0.001346881],"genre_scores_gemma":[0.9957427,0.001918304,0.0007875172,0.00002721604,0.000005576915,0.000009480584,0.0001021651,0.0000046401,0.001402389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001342343,"threshold_uncertainty_score":0.004364014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008234043052796458,"score_gpt":0.190921114885263,"score_spread":0.1826870718324665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}