{"id":"W2792182131","doi":"10.1074/jbc.r117.803064","title":"Lafora disease offers a unique window into neuronal glycogen metabolism","year":2018,"lang":"en","type":"review","venue":"Journal of Biological Chemistry","topic":"Glycogen Storage Diseases and Myoclonus","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Diabetes and Digestive and Kidney Diseases; National Science Foundation; Ministerio de Asuntos Económicos y Transformación Digital, Gobierno de España; National Institutes of Health; Ministerio de Economía y Competitividad; Mizutani Foundation for Glycoscience","keywords":"Lafora disease; Glycogen storage disease; Glycogen; Metabolism; Neuroscience; Disease; Carbohydrate metabolism; Window (computing); Biology; Biochemistry; Chemistry; Medicine; Internal medicine; Computer science; Enzyme; Phosphatase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003098058,0.0005376629,0.0007564194,0.001797924,0.0002349827,0.000802449,0.0005066569,0.0008604312,0.004255048],"category_scores_gemma":[0.0006423659,0.0001577568,0.0003457484,0.001097488,0.000268329,0.001273315,0.000570714,0.00131797,0.001726609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004480687,"about_ca_system_score_gemma":0.0008022743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006031888,"about_ca_topic_score_gemma":0.00130326,"domain_scores_codex":[0.9998882,0.00001602549,0.00002000457,0.00001829893,0.00004301679,0.0000144538],"domain_scores_gemma":[0.9997883,0.00008315843,0.00003032085,0.000006405222,0.00006303041,0.0000287537],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007017169,0.00003744054,0.000260209,0.0119191,0.0000909691,0.0005451241,0.00009061341,0.0001903027,0.00274028,0.004562921,0.0731063,0.9063867],"study_design_scores_gemma":[0.000007408756,0.00004023324,0.0005701987,0.00188183,0.00006534543,0.002066635,0.00004061319,0.00003226253,0.0003222242,0.00141152,0.9935514,0.00001039482],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001375052,0.99734,0.000112282,0.0006546665,0.0004633649,0.000002419516,0.00002250606,0.00001421374,0.001253056],"genre_scores_gemma":[0.00102369,0.9968435,0.0001701411,0.0004057228,0.0005628664,0.000003863703,0.00003902004,0.000002337363,0.000948842],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004255048,"threshold_uncertainty_score":0.0142346,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04927734996376888,"score_gpt":0.330130368476542,"score_spread":0.2808530185127731,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}