{"id":"W2792206222","doi":"10.1016/j.biotechadv.2018.01.008","title":"RNA interference technology to improve the baculovirus-insect cell expression system","year":2018,"lang":"en","type":"review","venue":"Biotechnology Advances","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"RNA interference; Gene silencing; Computational biology; Biotechnology; Biology; Recombinant DNA; Function (biology); Computer science; Gene; RNA; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005553746,0.000789164,0.00097922,0.001239392,0.0002101624,0.0009185467,0.0008226979,0.0007069012,0.001534146],"category_scores_gemma":[0.0003479054,0.0002606898,0.0004517036,0.001433344,0.0004096551,0.0008048479,0.0004479845,0.001934788,0.001196745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006313403,"about_ca_system_score_gemma":0.0007382969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007109627,"about_ca_topic_score_gemma":0.001011927,"domain_scores_codex":[0.9997904,0.00002256028,0.00002395312,0.00003542061,0.0001075722,0.00002014318],"domain_scores_gemma":[0.9998475,0.00006666304,0.0000225389,0.000007113931,0.00004434067,0.00001182981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001127316,0.0001074443,0.0003328203,0.01628205,0.0001015545,0.000349695,0.00008999291,0.0005825146,0.1028768,0.01204357,0.01665253,0.8504683],"study_design_scores_gemma":[0.00001788332,0.00009638614,0.0008277464,0.000646021,0.0001496404,0.0008418735,0.0000297517,0.0002950975,0.02858275,0.001653409,0.9668279,0.00003142502],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009151921,0.9909111,0.003634534,0.0003770231,0.0004710434,0.00002039135,0.00006618501,0.00005609218,0.003548434],"genre_scores_gemma":[0.004879647,0.9884398,0.003380563,0.0003776471,0.0001863085,0.00003060344,0.0001987551,0.00001310034,0.002493533],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001534146,"threshold_uncertainty_score":0.005132198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01397323336645029,"score_gpt":0.3048543626194929,"score_spread":0.2908811292530427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}