{"id":"W2792257754","doi":"10.1158/1538-7445.sabcs17-p2-10-07","title":"Abstract P2-10-07: A prospective clinical utility study of the impact of the 21-gene recurrence score (RS) assay in the treatment of estrogen receptor positive (ER+), HER2 negative (HER2-), 1-3 node positive (N+) breast cancer (BC)","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Internal medicine; Stage (stratigraphy); Cancer; Clinical trial; Prospective cohort study; Oncology; Hormonal therapy; Breast cancer; Estrogen receptor; Gynecology; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01198622,0.0009502101,0.0007043506,0.0003393537,0.0005560979,0.000954623,0.0008431186,0.001176207,0.004285178],"category_scores_gemma":[0.01670794,0.0005441637,0.0009216544,0.0005641569,0.001061409,0.0009398265,0.0006699868,0.001742051,0.001109504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008780454,"about_ca_system_score_gemma":0.001613774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002141825,"about_ca_topic_score_gemma":0.002119366,"domain_scores_codex":[0.9926483,0.00600257,0.0002119344,0.0005404833,0.0004291952,0.0001675304],"domain_scores_gemma":[0.9801339,0.01083792,0.003426215,0.001425901,0.001274129,0.002901965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.5838916,0.03475308,0.3531847,0.0002512442,0.001248344,0.0001961904,0.0003195837,0.001671819,0.00241668,0.0001595848,0.002209706,0.01969751],"study_design_scores_gemma":[0.1054543,0.517446,0.364911,0.00004147839,0.001311628,0.0004014953,0.000232718,0.006644036,0.001622191,0.0001587194,0.001687184,0.00008926896],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968141,0.0001203338,0.0003260121,0.0001482113,0.00002963669,0.0009761894,0.0008006302,0.00001864779,0.0007663024],"genre_scores_gemma":[0.9966089,0.0000744168,0.0006787983,0.0001808584,0.00007064951,0.0008799593,0.001004996,0.00001016817,0.0004912778],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01198622,"threshold_uncertainty_score":0.0633899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07061136293116974,"score_gpt":0.4396268728493783,"score_spread":0.3690155099182085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}