{"id":"W2792344809","doi":"10.1016/j.clcc.2018.03.001","title":"A Randomized Phase II Study of FOLFOX6/Bevacizumab With or Without Pelareorep in Patients With Metastatic Colorectal Cancer: IND.210, a Canadian Cancer Trials Group Trial","year":2018,"lang":"en","type":"article","venue":"Clinical Colorectal Cancer","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University; Juravinski Cancer Centre; Sunnybrook Health Science Centre; Queen's University; Ottawa Hospital; Saskatchewan Cancer Agency; Western University; University of Calgary; Princess Margaret Cancer Centre; BC Cancer Agency; McGill University; University of Ottawa","funders":"Canadian Cancer Society Research Institute; Oncolytics Biotech","keywords":"Medicine; Bevacizumab; Colorectal cancer; Oncology; Internal medicine; Randomized controlled trial; Cancer; Chemotherapy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001375633,0.001406093,0.001999939,0.0003020355,0.0005140437,0.0008774173,0.0008646828,0.001180193,0.006401452],"category_scores_gemma":[0.001133731,0.000515179,0.001396343,0.0004049391,0.001093787,0.0006818693,0.0003196198,0.002775065,0.0008881446],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001972402,"about_ca_system_score_gemma":0.003319136,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0117539,"about_ca_topic_score_gemma":0.04020386,"domain_scores_codex":[0.9995988,0.0001673682,0.00001266008,0.00006930101,0.00004110862,0.000110854],"domain_scores_gemma":[0.9994117,0.0001160152,0.00009842981,0.00004760463,0.00003975198,0.0002864988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9596614,0.004632297,0.0008012686,0.0004446279,0.0008098026,0.00003709716,0.00004859051,0.0004881269,0.002651736,0.0002167354,0.003574893,0.02663352],"study_design_scores_gemma":[0.9526933,0.04239447,0.002110881,0.00002676892,0.0004339812,0.00003835257,0.00002757065,0.0003315331,0.0002663503,0.0001831486,0.001475929,0.00001774769],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.978413,0.005030481,0.0006638572,0.002121578,0.0006384375,0.003684322,0.003143662,0.0001817271,0.006122871],"genre_scores_gemma":[0.9767472,0.003017112,0.002063315,0.002591366,0.000374467,0.003196553,0.003970682,0.0000442066,0.007995031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9882461,"threshold_uncertainty_score":0.02337098,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07572923921422868,"score_gpt":0.439881470559381,"score_spread":0.3641522313451523,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}