{"id":"W2792356983","doi":"10.1016/j.transci.2018.02.005","title":"Solvent-Detergent Plasma for the Treatment of Thrombotic Microangiopathies: A Canadian Tertiary Care Centre Experience","year":2018,"lang":"en","type":"article","venue":"Transfusion and Apheresis Science","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Vancouver General Hospital","funders":"","keywords":"Thrombotic thrombocytopenic purpura; Fresh frozen plasma; Tertiary care; Tolerability; Medicine; Hypogammaglobulinemia; Internal medicine; Immunology; Gastroenterology; Intensive care medicine; Platelet; Antibody; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000531839,0.0005441484,0.0004281074,0.0004869725,0.004075799,0.001220819,0.001114879,0.001084642,0.003062443],"category_scores_gemma":[0.00194549,0.0002349386,0.0003886711,0.001446626,0.0009206363,0.0003229768,0.0006979699,0.001062963,0.0003658735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01268904,"about_ca_system_score_gemma":0.01836073,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.6052043,"about_ca_topic_score_gemma":0.800932,"domain_scores_codex":[0.9994467,0.00007590933,0.00003520977,0.00004676518,0.0002021309,0.0001931883],"domain_scores_gemma":[0.9985319,0.0001717831,0.0001047781,0.00003393713,0.0004402087,0.000717356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.00499887,0.008361417,0.284761,0.001974481,0.0004377651,0.1883384,0.03222918,0.003273713,0.03277769,0.005892485,0.0414095,0.3955455],"study_design_scores_gemma":[0.001205535,0.008021618,0.6866767,0.00101516,0.000472807,0.1720088,0.02370041,0.003132885,0.007177022,0.001074926,0.09514008,0.0003740434],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9582442,0.0139088,0.001196615,0.004581172,0.0002142991,0.000326937,0.0002195774,0.00003966706,0.02126872],"genre_scores_gemma":[0.9755365,0.01243741,0.002900042,0.001970764,0.0001752845,0.000033813,0.0002524487,0.00004632739,0.006647455],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3947957,"threshold_uncertainty_score":0.7942415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.018742223504746,"score_gpt":0.2655751976758147,"score_spread":0.2468329741710687,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}