{"id":"W2792372978","doi":"10.1093/jcag/gwy008.210","title":"A209 XENOBIOTIC RECEPTOR REGULATION OF CLOSTRIDIUM DIFFICILE-ASSOCIATED TISSUE DAMAGE AND INFLAMMATION","year":2018,"lang":"en","type":"article","venue":"Journal of the Canadian Association of Gastroenterology","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Pregnane X receptor; Clostridium difficile toxin A; Chemokine; Inflammation; Clostridium difficile toxin B; Microbiology; Interleukin 8; Caco-2; In vivo; Receptor; Toxin; Biology; Cytokine; Pharmacology; Chemistry; In vitro; Immunology; Antibiotics; Clostridium difficile; Biochemistry; Nuclear receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001039023,0.0002348269,0.0001994733,0.000183935,0.000161511,0.0002778553,0.0001062706,0.0002561483,0.002743162],"category_scores_gemma":[0.00008269706,0.0001010463,0.0003141913,0.0001494588,0.0001813136,0.0001345637,0.000169048,0.000369808,0.0006640902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002650008,"about_ca_system_score_gemma":0.0002225744,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007219116,"about_ca_topic_score_gemma":0.0009201523,"domain_scores_codex":[0.9998537,0.00002883519,0.00001048138,0.0000230998,0.0000352521,0.00004859026],"domain_scores_gemma":[0.9999393,0.000005740237,0.00002150936,0.000005060478,0.000009919611,0.00001855599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003264199,0.00003356121,0.0003711926,0.00008181803,0.000006197647,0.0001307714,0.000008846415,0.00004033727,0.9970897,0.00008104054,0.0001137535,0.001716508],"study_design_scores_gemma":[0.0001187934,0.002829688,0.09558605,0.00005845556,0.0000650445,0.002624283,0.0002036233,0.001201887,0.8757932,0.0002255074,0.02126931,0.00002419612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9691117,0.02317132,0.002201023,0.0005537557,0.0001051102,0.00005705344,0.0008038639,0.00009540669,0.003900796],"genre_scores_gemma":[0.9840817,0.007977437,0.001446539,0.0001711303,0.00004086822,0.00004501047,0.0007157888,0.00001207505,0.005509544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002743162,"threshold_uncertainty_score":0.009176791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005382120430347458,"score_gpt":0.2296510078047077,"score_spread":0.2242688873743603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}